Trial Outcomes & Findings for Effects of a Compliant Arm Support on Post-stroke Upper Extremity Range of Motion (NCT NCT03867838)

NCT ID: NCT03867838

Last Updated: 2021-02-23

Results Overview

Reachable workspace was measured using a PhaseSpace motion capture system, recorded as an area (in square meters).

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

6 participants

Primary outcome timeframe

baseline, while using support device, and 30 minutes following removal of support device (up to 4 minutes per assessment)

Results posted on

2021-02-23

Participant Flow

Participants were screened to include only those whose most recent stroke occurred more than 6 months before the study date and to exclude those with conflating health problems, sensory deficits, or that experience pain during passive movements of the arm.

Participant milestones

Participant milestones
Measure
All Participants
Stroke survivors with upper extremity motor impairments
Overall Study
STARTED
6
Overall Study
COMPLETED
6
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
All Participants
n=6 Participants
Stroke survivors with upper extremity motor impairments
Age, Continuous
51 years
STANDARD_DEVIATION 10 • n=6 Participants
Sex: Female, Male
Female
2 Participants
n=6 Participants
Sex: Female, Male
Male
4 Participants
n=6 Participants
Fugl-Meyer Assessment of sensorimotor function
27 units on a scale
STANDARD_DEVIATION 13 • n=6 Participants
Correct scapulohumeral rhythm
6 Participants
n=6 Participants
Spatial neglect
0 Participants
n=6 Participants
Reachable workspace
0.10 m^2
STANDARD_DEVIATION 0.11 • n=6 Participants
Biceps activation
0.19 mV
STANDARD_DEVIATION 0.25 • n=6 Participants

PRIMARY outcome

Timeframe: baseline, while using support device, and 30 minutes following removal of support device (up to 4 minutes per assessment)

Reachable workspace was measured using a PhaseSpace motion capture system, recorded as an area (in square meters).

Outcome measures

Outcome measures
Measure
All Participants
n=6 Participants
Stroke survivors with upper extremity motor impairments
Percent Change From Baseline in Reachable Workspace
On support device
27 percent change
Standard Deviation 84
Percent Change From Baseline in Reachable Workspace
Post support device
-71 percent change
Standard Deviation 41

SECONDARY outcome

Timeframe: baseline and while using support device (up to 10 seconds per assessment)

Biceps activation measured using surface electromyography during an isometric hold to approximate the contributions of erroneous flexor synergies.

Outcome measures

Outcome measures
Measure
All Participants
n=6 Participants
Stroke survivors with upper extremity motor impairments
Percent Change From Baseline in Biceps Activation
-16 percent change
Standard Deviation 71

Adverse Events

All Participants

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Cole Simpson

Stanford University

Phone: 4049077708

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place