Medico-economics and QoL of Obese Patients Followed by Medical Analysis Laboratories (BIOSAOS )

Summary

Obesity is a major risk factor for obstructive sleep apnea (OSA). However, OSA is still largely under diagnosed in patients with a high cardiovascular risk. In this population the STOP-BANG questionnaire facilitates OSA screening. Moreover, blood bicarbonate concentration is a simple tool to screen for chronic respiratory disease and if elevated, is a marker of cardiometabolic comorbidities in obese patients. A combination of blood bicarbonate concentration and STOP BANG score could provide a cost-effective method of screening for OSA in obese patients. Such screening could enable earlier management and might significantly reduce the costs of treatment and improve the quality of life of patients at 2 years.

Conditions

• Obesity Hypoventilation Syndrome
• Obstructive Sleep Apnea

Interventions

OTHER

Care pathway

Screening for OSA using a combination of bicarbonate assay and STOP-BANG questionnaire and further management by a pneumologist as necessary

Sponsors & Collaborators

• University Hospital, Angers

  collaborator OTHER_GOV

• Poitiers University Hospital

  collaborator OTHER

• Union hospital, Toulouse

  collaborator UNKNOWN

• Hospital Alpes Leman, Annemasse

  collaborator UNKNOWN

• Hospital La Louvière, Lille

  collaborator UNKNOWN

• Oriade Laboratory, Vizille

  collaborator UNKNOWN

• Cerballiance laboratories, Lille

  collaborator UNKNOWN

• Oriade laboratory, Annemasse

  collaborator UNKNOWN

• University Hospital, Grenoble

  lead OTHER

Principal Investigators

• Jean-Louis PEPIN, MD, PhD · Grenoble Alpes University Hospital

Study Design

Allocation

RANDOMIZED

Purpose

SCREENING

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2019-09-14

Primary Completion

2022-12-06

Completion

2022-12-06

Countries

• France

Study Locations