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Comparison of Phenylephrine and Ephedrine in the Treatment of Hemodynamic Disorders After Spinal Anesthesia in the Elderly

NCT03858465 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2023-02-24

No results posted yet for this study

Summary

Spinal anesthesia is often used for lower limb surgery in elderly. Hypotension is a side effect of spinal block. In this study, intravenous ephedrine and phenylephrine will be compared with each other to prevent spinal anesthesia-induced hypotension, which is defined in absolute terms as a systolic blood pressure \< 100 mmHg or in relative terms as a 20% fall of systolic blood pressure from baseline.

Conditions

  • Hip Fractures
  • Elderly Patients
  • Spinal Anesthesia
  • Lower Limb Surgery

Interventions

DRUG

Ephedrine

intravenous 25 mg of ephedrine

DRUG

Phenylephrine

intravenous 0,3 mg of phenylephrine

Sponsors & Collaborators

  • Medical University of Warsaw

    lead OTHER

Principal Investigators

  • Rafał Kowalczyk, PhD · I Department of Anaesthesiology and Intensive Care, Infant Jesus Teaching Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-02-01
Primary Completion
2019-02-24
Completion
2023-02-01

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03858465 on ClinicalTrials.gov