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Analgesic Effect Of Intra-articular Bupivacaine Fentanyl for Postoperative Pain Relief in Knee Arthroscopic Surgery

NCT03847792 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 87

Last updated 2020-09-11

No results posted yet for this study

Summary

However, local anesthetic agents can produce analgesia for a limited time when used as a single injection. Bupivacaine is a local anesthetic that has an immediate action on pain by blocking peripheral afferents. However, as the ideal analgesic, the drug must cover the whole postoperative period (≥ 24 hours); therefore, bupivacaine is usually combined with many adjutants to provide long-lasting post-arthroscopy analgesia.

Conditions

  • Knee Arthroscopic Surgery

Interventions

DRUG

Group DB/Dexamethasone-Bupivacaine

The patient were received an intra-articular injection of 18ml bupivacaine 0.25% added to 8mg dexamethasone.

DRUG

Group FB /Fentanyl-Bupivacaine

The patient were received an intra-articular injection of 1 ug/kg fentanyl added to 18ml of 0.25% bupivacaine.

DRUG

Group PB/Placebo-Bupivacaine

Patients were received an intra-articular injection of 2ml isotonic saline added to 18ml of 0.25% bupivacaine.

Sponsors & Collaborators

  • Mansoura University

    lead OTHER

Principal Investigators

  • Mohamed M Sultan, MD · Professor of Anaesthesia and Surgical Intensive Care

  • Hazem ESM Weheba, MD · Assistant Professor of Anaesthesia and Surgical Intensive Care

  • Hosam Ibrahim EL said saber, MD · Lecturer of Anaesthesia and Surgical Intensive Care

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-03-31
Primary Completion
2020-05-30
Completion
2020-06-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03847792 on ClinicalTrials.gov