MedTrace Logo

Improving HIV/Tuberculosis Outcomes in Irkutsk

NCT03819374 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 53

Last updated 2022-03-09

No results posted yet for this study

Summary

The investigators propose to examine the prospective influence of substance use patterns on HIV/tuberculosis adherence, pharmacokinetics and disease progression while developing novel methods for early detection and correction of these mechanisms of treatment failure in Irkutsk. At the University of Virginia, the investigators have considerable research experience with vulnerable HIV populations and have adapted mobile phone methods for data collection of adherence, substance use, and study retention. The investigators have also begun development of colorimetric methods for pharmacokinetic monitoring that utilizes urine which may be suitable as a non-invasive sample for the unique environmental factors affecting HIV patients in Irkutsk, namely geographic remoteness and concurrent substance use

Conditions

Sponsors & Collaborators

  • National Institute on Drug Abuse (NIDA)

    collaborator NIH

  • Scientific Center for Family Health and Human Reproduction Problems, Russia

    collaborator OTHER_GOV

  • University of Virginia

    lead OTHER

Principal Investigators

  • Scott K Heysell · University of Virginia

Eligibility

Min Age
18 Years
Max Age
64 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-04-15
Primary Completion
2020-05-30
Completion
2021-04-30

Countries

  • Russia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03819374 on ClinicalTrials.gov