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Iron and Pollen Allergy in Women

NCT03816800 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 58

Last updated 2021-09-05

No results posted yet for this study

Summary

Iron deficiency and anemia are clearly associated with the onset of allergy and allergic diseases, whereas an improved iron status seems to prevent the onset of allergy in humans. Iron-deficiency can be absolute or functional. Functional iron-deficiency occurs during immune activation and may be reflective for the hyperactive state of atopic subjects.

The investigators plan a prophylactic dietary intervention study in atopic/allergic and non-allergic individuals that transport chelated iron to immune cells. Over the course of six months, oral supplementation of placebo or whey protein-bound chelated iron will be given and 1) clinical reactivity 2) iron status and 3) changes in the microflora due to the treatment will be assessed.

Conditions

  • Allergy Pollen
  • Healthy

Interventions

DIETARY_SUPPLEMENT

ImmunoBon

The dietary agent contains vitamin A, Zn, chelated iron and whey proteins.

DIETARY_SUPPLEMENT

Placebo

the dietary agent does not contain vitamin A, Zn, chelated iron and whey proteins

Sponsors & Collaborators

  • Medical University of Vienna

    lead OTHER

Principal Investigators

  • Franziska Roth-Walter, PhD · The interuniversity Messerli Research Institute

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-01-28
Primary Completion
2020-10-28
Completion
2020-10-29

Countries

  • Austria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03816800 on ClinicalTrials.gov