A Study of CS1003 in Subjects With Advanced Solid Tumors or Lymphomas
NCT03809767 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 107
Last updated 2022-11-30
Summary
This is a phase Ia/Ib, open-label, multiple-dose, dose-escalation and expansion study to evaluate the safety, tolerability, pharmacokinetics and anti-tumor activity of CS1003 in subjects with advanced solid tumors or lymphoma.
Conditions
Interventions
- DRUG
-
CS1003 monoclonal antibody
CS1003 will be administered intravenously every 3 weeks.
Sponsors & Collaborators
- lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-10-29
- Primary Completion
- 2021-08-30
- Completion
- 2022-06-13
Countries
- China
Study Locations
More Related Trials
-
A Phase 1, Open-label, Multicenter, Dose Escalation Study of IBI363 (PD1-IL2m) in Subjects With Advanced Solid Malignancies or Lymphomas
NCT05290597 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Phase 1 Study of Anti-PD-L1 Monoclonal Antibody KN035 to Treat Locally Advanced or Metastatic Solid Tumors
NCT02827968 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I Study of QLP2117 in Subjects With Advanced Solid Tumors
NCT05830045 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of JNJ-70218902 in Participants With Advanced Stage Solid Tumors
NCT04397276 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability, and Immunogenicity of mRNA-4157 Alone and in Combination in Participants With Solid Tumors
NCT03313778 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of CD-001 in Patients With Advanced Solid Tumors
NCT06801470 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of ICP-033 in Patients With Advanced Solid Tumors
NCT05367232 ·Status: RECRUITING ·Phase: PHASE1
-
A Study to Test Different Doses of BI 1831169 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)
NCT05155332 ·Status: SUSPENDED ·Phase: PHASE1
-
Study of CS3006 in Subjects With Locally Advanced or Metastatic Solid Tumors
NCT03736850 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I/II Study of CS2009 in Participants With Advanced Solid Tumors
NCT06741644 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Clinical Study on LM103 Injection for the Treatment of Advanced Solid Tumors
NCT05971589 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
A Study to Investigate ANS03 in Participants With Locally Advanced or Metastatic Solid Tumors
NCT06716138 ·Status: RECRUITING ·Phase: PHASE1
-
KN046 in Subjects With Advanced Solid Tumors and Lymphoma
NCT03733951 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I Study of QLS12004 in Patients With Advanced Solid Tumors
NCT05829616 ·Status: UNKNOWN ·Phase: PHASE1
-
A Phase 1 Study to Investigate FP008 in Subjects With Advanced Solid Tumors
NCT06990698 ·Status: RECRUITING ·Phase: PHASE1
-
A Phase 1 Study of BPI-371153 in Subjects with Advanced Solid Tumors or Relapsed/Refractory Lymphoma
NCT05341557 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of KC1036 in Patients with Advanced Solid Tumors
NCT04387916 ·Status: RECRUITING ·Phase: PHASE1
-
QLF32004 Injection for the Treatment of Patients With Advanced Malignant Tumors
NCT05108779 ·Status: UNKNOWN ·Phase: PHASE1
-
A Phase Ia Clinical Study of QLF31907 Injection in Patients With Advanced Malignant Tumors
NCT05150405 ·Status: RECRUITING ·Phase: PHASE1
-
Study of STI-3031 in Patients With Selected Relapsed or Refractory Solid Tumors
NCT04809012 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Study of ES002023 (Anti-CD39 Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors
NCT05075564 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of CBP-1008 in Patients With Advanced Solid Tumor
NCT04740398 ·Status: RECRUITING ·Phase: PHASE1
-
A Phase I Study to Assess the Safety and Tolerability of BL0006 for Patients With Advanced Solid Tumours
NCT06247657 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of NB003 in Patients With Advanced Malignancies
NCT04936178 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of QLF3108 in Participants With Advanced Solid Tumor
NCT06019013 ·Status: RECRUITING ·Phase: PHASE1