Pre- and Post-Operative Exercise Program in Upper Gastrointestinal Cancers

Summary

Esophageal and gastric cancers are a considerable health burden. In the past 10 years the 5-year survival for both cancers has doubled. This is due to a number of factors including advances in neo adjuvant and adjuvant chemotherapy and radiotherapy. However, physical fitness significantly declines as a result of neo adjuvant an adjuvant therapy. From studies in other cancers it is known that peri operative training improves physical fitness, yet there is little research into its effects in those with upper gastrointestinal cancers. The aim of this study is to assess the effect of a pre-and post operative training program on patients with upper gastrointestinal cancers on their physical fitness and consequently their optimism, quality of life and post operative morbidity.

Conditions

• Exercise Intervention

Interventions

BEHAVIORAL

Standard Exercise Program

Standard Exercise Program- Participants will be invited to take part in a structured home, supervised, or both, exercise program while undergoing neo adjuvant therapy and for a six week period when deemed fit post surgery.

Sponsors & Collaborators

• Beaumont Hospital

  collaborator OTHER

• Mercy University Hospital, Cork, Ireland

  collaborator OTHER

• Dublin City University

  collaborator OTHER

• Royal College of Surgeons, Ireland

  lead OTHER

Principal Investigators

• William Robb, MB,BCh,BAO,BA,FRCSI,MD · Beaumont Hospital Dublin

• Noel McCaffrey, MB,BCh,BAO,BSc,MSc · Dublin City University

• Thomas Murphy, MB,BCh,BAO,FRCSI · Mercy University Hospital, Cork

• Jarlath Bolger, MB,BCh,BAO,MD · Beaumont Hospital

• Pamela Gallagher, Professor of Psychology · Dublin City University

• Claire Timon, BSc,PhD · University College Dublin

• Jan Sorensen, MSc, MA · Royal College of Surgeons, Ireland

Study Design

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2019-03-01

Primary Completion

2020-12-19

Completion

2021-03-01

Countries

• Ireland

Study Locations