MedTrace Logo

Fecal Microbiota Transplantation for Ulcerative Colitis

NCT03804931 · Status: RECRUITING · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2019-01-15

No results posted yet for this study

Summary

Fecal microbiota transplantation (FMT) is a strategy that infuses a fecal suspension containing a healthy donor's microbiota into a patient's gut to restore his/her intestinal microbiome. Fecal microbiota transplantation has been used for several disease，but the efficacy of ulcerative colitis(UC) by fecal microbiota transplantation needs to be further explored.The investigators propose to determine the efficiency and safety of FMT in patients with ulcerative colitis(UC).

Conditions

Interventions

PROCEDURE

Fecal microbiota transplantation

200 mL of prepared fecal microbiota suspension from healthy donors' fresh feces was injected into the intestine

PROCEDURE

Infusion of Saline

Infusion of Saline

DRUG

5-Aminosalicylic acid(5-ASA) and/or Prednisone

Mesalazine and/or Prednisone

Sponsors & Collaborators

  • Guangzhou First People's Hospital

    lead OTHER

Principal Investigators

  • Yuqiang Nie, MD · Guangzhou First People's Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-01-20
Primary Completion
2028-12-31
Completion
2030-12-31

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03804931 on ClinicalTrials.gov