Does Myomectomy for Intramural Fibroid Improve ART Outcome?

Summary

Intamural fibroids (myoma) do exist in some infertile women undergoing IVF treatment. There is controversy whether myomectomy before IVF treatment could improve IVF outcome. This trial will examine whether myomectomy in those patients could improve the results.

Conditions

• Fibroid Uterus

Interventions

PROCEDURE

Myomectomy

This study will include women who have intramural myomas ranging from 3-5 cm The participants will be randomly allocated into two groups. In group (1): myomectomy will be performed before ART In group (2):women will have their trial of ART without myomectomy In group A, ART will be performed 3 months after myomectomy if the uterine cavity is not opened and 6 months after myomectomy upon inadvertent opening of the uterine cavity during surgery

Sponsors & Collaborators

• Alexandria University

  collaborator OTHER

• Zagazig University

  collaborator OTHER_GOV

• Sohag University

  collaborator OTHER

• Assiut University

  collaborator OTHER

• Mansoura University

  lead OTHER

Principal Investigators

• Ahmed Gibreel, MD · Mansoura University

• Mohamed S Abdelhafez, MD · Mansoura University

• Salah Rasheed, MD · Sohag University

• Ahmed Nasr, MD · Assiut Universit

• Hisham A Saleh, MD · Alexandria University

• Hassan El Maghraby, MD · Alexandria University

• Eman El Gindy, MD · Zagazig University

• Hoda Sibai, MD · Zagazig University

• Hamed Yossef, MD · Mansoura University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

35 Years

Sex

FEMALE

Healthy Volunteers

No

Timeline & Regulatory

Start

2019-12-01

Primary Completion

2021-04-30

Completion

2021-04-30

Countries

• Egypt

Study Locations