Identification of Allergic Asthmatics Reactive to Felis Catus (Cat Hair) Allergen Inhalation
NCT03780387 · Status: TERMINATED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 1
Last updated 2022-10-18
Summary
This study is designed to identify Felis Catus, or cat hair, sensitive asthmatics who demonstrate a late phase asthmatic response after cat hair inhalation. These subjects may be invited to participate in a planned future study investigating novel asthma treatments.
Conditions
- Asthma Atopic
Interventions
- BIOLOGICAL
-
Felis Catus
Inhalation of Felis Catus allergen in subjects allergic to Felis Catus
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
collaborator NIH -
University of North Carolina, Chapel Hill
lead OTHER
Principal Investigators
-
Michelle Hernandez, MD · University of North Carolina, Chapel Hill
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-04-16
- Primary Completion
- 2019-11-11
- Completion
- 2019-11-11
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Ability of a Cat Food to Reduce Respiratory Symptoms in Cat Allergic Patients
NCT05656482 ·Status: UNKNOWN
-
A Study on the Efficacy of Environmental Probiotics in Patients With Cat Hair Allergies
NCT07114133 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Study in Cat-Allergic Patients With Asthma to Evaluate the Efficacy of a Single Dose of REGN1908-1909 to Reduce Bronchoconstriction Upon Cat Allergen Challenge
NCT03838731 ·Status: COMPLETED ·Phase: PHASE2
-
Exposure Chamber Trial With Cat Immunotherapy
NCT00987909 ·Status: COMPLETED ·Phase: PHASE2
-
Early Phase Administration of Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation
NCT03513471 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Evaluation of the Effect of a Nasal Allergen Challenge With Dermatophagoides Farinae Extract on Nasal Airway Inflammation in Allergic Individuals, Comparing E-cigarette Users to Cigarette Smokers and Non-smokers.
NCT03023397 ·Status: TERMINATED ·Phase: PHASE1
-
Evaluation of a New Self-assessed, Home-based Symptom Score in Cat Allergic Patients
NCT02959073 ·Status: TERMINATED
-
A Single-Center, Randomized, Double-Blind, Placebo-Controlled, Two-Way Crossover Study Designed to Evaluate the Efficacy of Fexofenadine HCl 180 mg for Preventing and Controlling Cat Allergy Symptoms
NCT00637884 ·Status: COMPLETED ·Phase: PHASE4
-
Late Phase Administration Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation
NCT03513458 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Crossover Study of Zafirlukast in Preventing Allergen-induced Signs and Symptoms in Response to Cat Dander Challenge
NCT06069063 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Study of MK0476 (Montelukast Sodium) and Effects on Asthma and Nasal Symptoms Upon Exposure to Cats (0476-256)
NCT00092105 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of a Nasal Allergen Challenge Procedure Using Dust Mite Extract
NCT00927329 ·Status: WITHDRAWN ·Phase: PHASE1
-
Study of Dust Mite Inhalation in Humans
NCT00448851 ·Status: COMPLETED ·Phase: PHASE1
-
Effectiveness of an Air Purifier on Asthmatic and Cat-allergic Subjects in the ALYATEC Environmental Exposure Chamber
NCT06691568 ·Status: COMPLETED ·Phase: NA
-
Impact of Pet Cats on Nasal and Gut Microbiota in Patients With Cat Allergen Allergy
NCT07110311 ·Status: RECRUITING
-
Red Maple Trials Cat Allergen Natural Exposure Chamber Validation in Cat-allergic Subjects
NCT03414801 ·Status: COMPLETED ·Phase: NA
-
Safety and Immunogenicity of Cat-allergen Intralymphatic Immunotherapy in Patients With Cat Allergy With and Without Asthma
NCT06960382 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Biomarkers in Nasal Samples of Seasonal Allergic Rhinitics
NCT04670627 ·Status: COMPLETED
-
Study to Assess the Safety and Effectiveness of Beltavac® Polymerized With Cat Dander
NCT04207697 ·Status: COMPLETED
-
Diesel Exhaust Particles and Leukotriene Production
NCT00915447 ·Status: WITHDRAWN
-
Treatment of Ragweed-Allergic Asthma With an Immunostimulatory Drug
NCT00318747 ·Status: TERMINATED ·Phase: PHASE2
-
Threshold Concentrations for Ragweed and Birch Pollen in Seasonal Allergic Rhinitis
NCT05346718 ·Status: COMPLETED ·Phase: NA
-
A Randomized Prospective Clinical Trial of Fel d 1 Peptide Immunotherapy
NCT02311413 ·Status: COMPLETED ·Phase: PHASE2
-
Effects of Multiple Nasal Exposures to House Dust Mite Allergen on Nasal and Body Inflammation and Airway Sensitivity
NCT00513487 ·Status: COMPLETED ·Phase: NA
-
Intralymphatic Immunotherapy for House Dust Mite, Dog, and Cat Allergy Using Tyrosine S® in Allergic Rhinitis
NCT02665754 ·Status: COMPLETED ·Phase: PHASE1