Trial Outcomes & Findings for Gas Exchange Kinetics and Work Load During Exercise (NCT NCT03770507)

NCT ID: NCT03770507

Last Updated: 2026-03-23

Results Overview

Breath by breath gas exchange VO2 in response to exercise.

Recruitment status

COMPLETED

Study phase

Target enrollment

94 participants

Primary outcome timeframe

At least 48 hours

Results posted on

2026-03-23

Participant Flow

Participant milestones

Participant milestones
Measure	Treadmill and Cyclo Ergometer Exercise in Children Comparison of gas exchange kinetics between treadmill and cyclo ergometer exercises Exercise Training: Comparison of stationary bike and treadmill exercise among children	Treadmill and Cyclo Ergometer Exercise in Adolescents Comparison of gas exchange kinetics between treadmill and cyclo ergometer exercises Exercise Training: Comparison of cyclo ergometer and treadmill exercise among adolescents	Treadmill and Cyclo Ergometer Exercise in Adults Comparison of gas exchange kinetics between treadmill and cyclo ergometer exercises Exercise Training: Comparison of cyclo ergometer and treadmill exercise among Adults
Overall Study STARTED	34	41	19
Overall Study COMPLETED	34	41	19
Overall Study NOT COMPLETED	0	0	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Gas Exchange Kinetics and Work Load During Exercise

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Treadmill and Cycle Ergometer Exercise in Children n=34 Participants Comparison of gas exchange kinetics between treadmill and cyclo ergometer exercises Exercise Training: Comparison of cyclo ergometer and treadmill exercise among children	Treadmill and Cycle Ergometer Exercise in Adolescents n=41 Participants Comparison of gas exchange kinetics between treadmill and cyclo ergometer exercises Exercise Training: Comparison of cyclo ergometer and treadmill exercise among Adolescents	Treadmill and Cycle Ergometer Exercise in Adults n=19 Participants Comparison of gas exchange kinetics between treadmill and cyclo ergometer exercises Exercise Training: Comparison of cyclo ergometer and treadmill exercise among Adults	Total n=94 Participants Total of all reporting groups
Age, Categorical <=18 years	34 Participants n=10 Participants	41 Participants n=8 Participants	0 Participants n=18 Participants	75 Participants n=158 Participants
Age, Categorical Between 18 and 65 years	0 Participants n=10 Participants	0 Participants n=8 Participants	19 Participants n=18 Participants	19 Participants n=158 Participants
Age, Categorical >=65 years	0 Participants n=10 Participants	0 Participants n=8 Participants	0 Participants n=18 Participants	0 Participants n=158 Participants
Age, Continuous	9.8 years STANDARD_DEVIATION 1.4 • n=10 Participants	16.2 years STANDARD_DEVIATION 1.6 • n=8 Participants	27.7 years STANDARD_DEVIATION 3.5 • n=18 Participants	17.9 years STANDARD_DEVIATION 2.1 • n=158 Participants
Sex: Female, Male Female	16 Participants n=10 Participants	23 Participants n=8 Participants	11 Participants n=18 Participants	50 Participants n=158 Participants
Sex: Female, Male Male	18 Participants n=10 Participants	18 Participants n=8 Participants	8 Participants n=18 Participants	44 Participants n=158 Participants
Race/Ethnicity, Customized Ethnicity (Hispanic/Latino)	1 Participants n=10 Participants	3 Participants n=8 Participants	0 Participants n=18 Participants	4 Participants n=158 Participants
Race/Ethnicity, Customized Race (White)	29 Participants n=10 Participants	24 Participants n=8 Participants	12 Participants n=18 Participants	65 Participants n=158 Participants
Race/Ethnicity, Customized Race (Asian)	3 Participants n=10 Participants	17 Participants n=8 Participants	6 Participants n=18 Participants	26 Participants n=158 Participants
Race/Ethnicity, Customized Race (African-American)	2 Participants n=10 Participants	0 Participants n=8 Participants	1 Participants n=18 Participants	3 Participants n=158 Participants
Region of Enrollment United States	34 participants n=10 Participants	41 participants n=8 Participants	19 participants n=18 Participants	94 participants n=158 Participants

PRIMARY outcome

Timeframe: At least 48 hours

Breath by breath gas exchange VO2 in response to exercise.

Outcome measures

Outcome measures
Measure	Cyclo Ergometer andTreadmill Exercise in Children n=34 Participants Comparison of submaximal CPET variables between treadmill and cyclo ergometer exercises among children	Cyclo Ergometer and Treadmill Exercise in Adolescents n=41 Participants Comparison of submaximal CPET variables between treadmill and cyclo ergometer exercises among adolescents	Cyclo Ergometer and Treadmill Exercise in Adults n=19 Participants Comparison of submaximal CPET variables between treadmill and cyclo ergometer exercises among adults
Maximum Oxygen Uptake (VO2) Measurements During Exercise Cyclo Ergometer Peak VO2 (L/min)	1.6 L/min Standard Deviation 0.4	2.8 L/min Standard Deviation 0.6	3.2 L/min Standard Deviation 0.8
Maximum Oxygen Uptake (VO2) Measurements During Exercise Treadmill Peak V02 (L/min)	1.7 L/min Standard Deviation 0.4	2.9 L/min Standard Deviation 0.5	3.5 L/min Standard Deviation 0.5

SECONDARY outcome

Timeframe: At least 48 hours

Heart Rate (HR) values in response to exercise