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Placement of Antibiotic Powder in Wounds During the Emergency Room

NCT03765567 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 200

Last updated 2025-08-01

No results posted yet for this study

Summary

This is the first prospective controlled study to determine whether the topical application of vancomycin powder reduces infection-related complications when applied to open fracture injuries in the acute emergency department setting.

Conditions

  • Open Fracture

Interventions

DRUG

Vancomycin

2 vials of Vancomycin 1g powder will be applied topically to the open fracture wound site.

Sponsors & Collaborators

  • United States Army Institute of Surgical Research

    collaborator FED

  • San Antonio Military Medical Center

    collaborator FED

  • The University of Texas Health Science Center at San Antonio

    lead OTHER

Principal Investigators

  • Robert A De Lorenzo, MD · University of Texas

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
89 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-10-05
Primary Completion
2026-07-31
Completion
2027-07-31
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03765567 on ClinicalTrials.gov