Trial Outcomes & Findings for Variability and Specificity in Reactive Stabilization Movements to Diverse Slip Perturbations (NCT NCT03755336)
NCT ID: NCT03755336
Last Updated: 2025-05-25
Results Overview
Percentage of trials which result in a fall. Falls are classified when the maximum force on the load cell in the harness system exceeds 30% body weight.
COMPLETED
NA
44 participants
Up to 7 days
2025-05-25
Participant Flow
Participant milestones
| Measure |
Slipping Perturbations - Younger Adults
The intervention involves exposing younger adult participants to a series of 12 unannounced slip perturbations while walking overground. These perturbations will be delivered at 3 different times within the gait cycle - early phase, middle phase, and late phase.
Administered Slip Perturbations: Slips will be administered in early, middle or late phases of stance during overground walking.
|
Slipping Perturbations - Older Adults
The intervention involves exposing older adult participants to a series of 12 unannounced slip perturbations while walking overground. These perturbations will be delivered at 3 different times within the gait cycle - early phase, middle phase, and late phase.
Administered Slip Perturbations: Slips will be administered in early, middle or late phases of stance during overground walking.
|
|---|---|---|
|
Overall Study
STARTED
|
22
|
22
|
|
Overall Study
COMPLETED
|
22
|
22
|
|
Overall Study
NOT COMPLETED
|
0
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Variability and Specificity in Reactive Stabilization Movements to Diverse Slip Perturbations
Baseline characteristics by cohort
| Measure |
Slipping Perturbations - Younger Adults
n=22 Participants
The intervention involves exposing younger adult participants to a series of 12 unannounced slip perturbations while walking overground. These perturbations will be delivered at 3 different times within the gait cycle - early phase, middle phase, and late phase.
Administered Slip Perturbations: Slips will be administered in early, middle or late phases of stance during overground walking.
|
Slipping Perturbations - Older Adults
n=22 Participants
The intervention involves exposing older adult participants to a series of 12 unannounced slip perturbations while walking overground. These perturbations will be delivered at 3 different times within the gait cycle - early phase, middle phase, and late phase.
Administered Slip Perturbations: Slips will be administered in early, middle or late phases of stance during overground walking.
|
Total
n=44 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Categorical
<=18 years
|
0 Participants
n=99 Participants
|
0 Participants
n=107 Participants
|
0 Participants
n=206 Participants
|
|
Age, Categorical
Between 18 and 65 years
|
22 Participants
n=99 Participants
|
0 Participants
n=107 Participants
|
22 Participants
n=206 Participants
|
|
Age, Categorical
>=65 years
|
0 Participants
n=99 Participants
|
22 Participants
n=107 Participants
|
22 Participants
n=206 Participants
|
|
Sex: Female, Male
Female
|
10 Participants
n=99 Participants
|
11 Participants
n=107 Participants
|
21 Participants
n=206 Participants
|
|
Sex: Female, Male
Male
|
12 Participants
n=99 Participants
|
11 Participants
n=107 Participants
|
23 Participants
n=206 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
1 Participants
n=99 Participants
|
0 Participants
n=107 Participants
|
1 Participants
n=206 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
21 Participants
n=99 Participants
|
22 Participants
n=107 Participants
|
43 Participants
n=206 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=99 Participants
|
0 Participants
n=107 Participants
|
0 Participants
n=206 Participants
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
0 Participants
n=99 Participants
|
0 Participants
n=107 Participants
|
0 Participants
n=206 Participants
|
|
Race (NIH/OMB)
Asian
|
6 Participants
n=99 Participants
|
0 Participants
n=107 Participants
|
6 Participants
n=206 Participants
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
0 Participants
n=99 Participants
|
0 Participants
n=107 Participants
|
0 Participants
n=206 Participants
|
|
Race (NIH/OMB)
Black or African American
|
1 Participants
n=99 Participants
|
0 Participants
n=107 Participants
|
1 Participants
n=206 Participants
|
|
Race (NIH/OMB)
White
|
15 Participants
n=99 Participants
|
22 Participants
n=107 Participants
|
37 Participants
n=206 Participants
|
|
Race (NIH/OMB)
More than one race
|
0 Participants
n=99 Participants
|
0 Participants
n=107 Participants
|
0 Participants
n=206 Participants
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=99 Participants
|
0 Participants
n=107 Participants
|
0 Participants
n=206 Participants
|
|
Height
|
171.3 centimeters
STANDARD_DEVIATION 15.2 • n=99 Participants
|
169.9 centimeters
STANDARD_DEVIATION 11.0 • n=107 Participants
|
170.6 centimeters
STANDARD_DEVIATION 13.0 • n=206 Participants
|
|
Weight
|
73.6 kilograms
STANDARD_DEVIATION 12.8 • n=99 Participants
|
81.3 kilograms
STANDARD_DEVIATION 17.3 • n=107 Participants
|
77.5 kilograms
STANDARD_DEVIATION 15.6 • n=206 Participants
|
PRIMARY outcome
Timeframe: Up to 7 daysPopulation: Participants were administered slips 12 times in a session for each of 3 sessions.
Percentage of trials which result in a fall. Falls are classified when the maximum force on the load cell in the harness system exceeds 30% body weight.
Outcome measures
| Measure |
Slipping Perturbations - Younger Adults
n=792 Trials
The intervention involves exposing younger adult participants to a series of 12 unannounced slip perturbations while walking overground. These perturbations will be delivered at 3 different times within the gait cycle - early phase, middle phase, and late phase.
Administered Slip Perturbations: Slips will be administered in early, middle or late phases of stance during overground walking.
|
Slipping Perturbations - Older Adults
n=792 Trials
The intervention involves exposing older adult participants to a series of 12 unannounced slip perturbations while walking overground. These perturbations will be delivered at 3 different times within the gait cycle - early phase, middle phase, and late phase.
Administered Slip Perturbations: Slips will be administered in early, middle or late phases of stance during overground walking.
|
|---|---|---|
|
Fall Rates
|
18.3 Percentage of trials resulting in falls.
|
16.0 Percentage of trials resulting in falls.
|
SECONDARY outcome
Timeframe: Up to 7 daysThe total displacement of the slipping foot from the point of administered slip perturbation, until the foot stops sliding is assessed.
Outcome measures
Outcome data not reported
SECONDARY outcome
Timeframe: Up to 7 daysAngular momentum of the trunk is assessed during the period of time from the onset of slip perturbation until the subject recovers or falls.
Outcome measures
Outcome data not reported
SECONDARY outcome
Timeframe: Up to 7 daysPosition of the placement of the swing foot relative to the center of mass in the transverse plane following slip perturbation will be assessed.
Outcome measures
Outcome data not reported
SECONDARY outcome
Timeframe: Up to 7 daysThe coefficient of variation of the time series of stride times during treadmill walking is assessed.
Outcome measures
Outcome data not reported
SECONDARY outcome
Timeframe: Up to 7 daysThe maximum velocity of the slipping foot will be assessed within the period from the administered slip perturbation, until the foot stops sliding.
Outcome measures
Outcome data not reported
SECONDARY outcome
Timeframe: Up to 7 daysTime of the placement of the swing foot relative to the onset of the administered slip perturbation is assessed
Outcome measures
Outcome data not reported
SECONDARY outcome
Timeframe: Up to 7 daysThe sample entropy of the time series of stride times during treadmill walking is assessed.
Outcome measures
Outcome data not reported
Adverse Events
Slipping Perturbations - Younger Adults
Slipping Perturbations - Older Adults
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place