DC Vaccine in Colorectal Cancer
NCT03730948 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 4
Last updated 2024-05-24
Summary
This is a pilot study to assess the safety and tolerability, as well as the immune response rate, of mDC3 vaccine in patients with colorectal cancer.
Conditions
Interventions
- BIOLOGICAL
-
DC vaccine
DC vaccine for colorectal cancer
Sponsors & Collaborators
-
Parker Institute for Cancer Immunotherapy
collaborator OTHER -
National Cancer Institute (NCI)
collaborator NIH - lead OTHER
Principal Investigators
-
Kim Reiss-Binder, MD · University of Pennsylvania
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-03-12
- Primary Completion
- 2022-02-22
- Completion
- 2022-12-01
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Dendritic Cell Vaccination in Patients With Lynch Syndrome or Colorectal Cancer With MSI
NCT01885702 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Immunotherapy in Treating Patients With Resected Liver Metastases From Colon Cancer
NCT00003433 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Pilot Trial of HER-2/Neu Pulsed DC1 Vaccine for Patients With HER-2 Positive Metastatic Cancer
NCT02473653 ·Status: NO_LONGER_AVAILABLE
-
Active Immunization of Patients With Carcinoma of Oral Cavity or Oropharynx With Autologous Dendritic Cells Transfected With DNA From Autologous Tumor
NCT00377247 ·Status: TERMINATED ·Phase: PHASE1
-
DC Vaccine for Patients With Ductal Carcinoma In Situ
NCT02061332 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study of Vaccination With Poly-ICLC and Dendritic Cells in Patients With Pancreatic Adenocarcinoma
NCT01677962 ·Status: COMPLETED ·Phase: PHASE1
-
Dendritic Cell Vaccine for Head and Neck Cancer
NCT00492947 ·Status: WITHDRAWN ·Phase: PHASE1
-
Dendritic Cell Vaccine Study (DC/PC3) for Prostate Cancer
NCT00345293 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Personalized DC Vaccine for Lung Cancer
NCT02956551 ·Status: UNKNOWN ·Phase: PHASE1
-
Tumor-Pulsed Dendritic Cells Used as a Tumor Vaccine
NCT00176761 ·Status: TERMINATED ·Phase: PHASE2
-
Safety and Efficacy Study of DCVax-Direct in Solid Tumors
NCT01882946 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Personalized DC Vaccine for Postoperative Cancer
NCT04147078 ·Status: RECRUITING ·Phase: PHASE1
-
Dendritic Cell Therapy for Brain Metastases From Breast- or Lung Cancer
NCT03638765 ·Status: UNKNOWN ·Phase: PHASE1
-
DC Vaccine Combined With IL-2 and IFNα-2a in Treating Patients With mRCC
NCT00085436 ·Status: COMPLETED ·Phase: PHASE2
-
Mature Dendritic Cell Vaccination Against Unique Immunogenic Peptides in Patients With Non Small Cell Lung Cancer (NSCLC)
NCT02419170 ·Status: WITHDRAWN ·Phase: EARLY_PHASE1
-
Vaccine Therapy in Treating Patients With Metastatic Prostate Cancer
NCT00010127 ·Status: TERMINATED ·Phase: PHASE1
-
Study With Dendritic Cell Immunotherapy in Resected Hepatic Metastasis of Colorectal Carcinoma
NCT01348256 ·Status: UNKNOWN ·Phase: PHASE2
-
PD-1 Alone or With Dendritic Cell/Renal Cell Carcinoma Fusion Cell Vaccine
NCT01441765 ·Status: TERMINATED ·Phase: PHASE2
-
Carcinoembryonic Antigen-loaded Dendritic Cells in Advanced Colorectal Cancer Patients
NCT00228189 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Personalized Vaccine Generated by Autologous Dendritic Cells Pulsed With Autologous Whole Tumor Cell Lysate Treat Advanced Solid Tumor Patients With High Tumor Mutation Burden
NCT03671720 ·Status: WITHDRAWN ·Phase: EARLY_PHASE1
-
Dendritic Cells (White Blood Cells) Vaccination for Advanced Melanoma
NCT00683670 ·Status: COMPLETED ·Phase: PHASE1
-
Dendritic Cells (DC) Vaccine for Metastatic Melanoma
NCT01042366 ·Status: TERMINATED ·Phase: PHASE2
-
Personalized Dendritic Cell Vaccine Pilot for High Risk TNBC After Neoadjuvant Therapy
NCT06435351 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
A Translational Study of Tumor Antigen-pulsed DC Vaccine for ESCC
NCT05317325 ·Status: UNKNOWN ·Phase: PHASE1
-
Denileukin Diftitox Followed by Vaccine Therapy in Treating Patients With Metastatic Cancer
NCT00128622 ·Status: COMPLETED ·Phase: PHASE1