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The Role of Hydrosalpinx in Recurrent Miscarriage

NCT03703401 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 137

Last updated 2022-11-16

No results posted yet for this study

Summary

Miscarriage affects one in five pregnancies and little progress has been made in understanding and treating this distressing condition. C. trachomatis is the most common sexually transmitted infection in the UK. C. trachomatis infection can have serious health consequences, including fallopian tube damage. Untreated C. trachomatis infection and tubal damage have been associated with miscarriage and adverse pregnancy outcomes such as preterm birth, low birth weight and stillbirth. A cohort study is needed to establish the prevalence of tubal disease in women with recurrent miscarriages. HyCoSy will be performed to identify tubal disease and establish the magnitude of the problem in the recurrent miscarriage population. The prognosis of tubal disease on miscarriage and other obstetric outcomes, and the role of medical interventions such as tubal surgery (to treat hydrosalpinx) on reducing miscarriage and adverse obstetric outcomes will also be studied.

Objectives

1. Establish the prevalence of hydrosalpinx in the recurrent miscarriage population.
2. Establish the prognosis of women diagnosed with recurrent miscarriage with concurrent hydrosalpinx.
3. Explore the role of tubal surgery for improving reproductive outcomes in women with recurrent miscarriage population and hydrosalpinx.

Conditions

  • Abortion, Spontaneous
  • Miscarriage, Recurrent
  • Hydrosalpinx

Interventions

DIAGNOSTIC_TEST

Hysterosalpingo-contrast-sonogram

A contrast ultrasound scan to examine fallopian tube pathology and blockage

Sponsors & Collaborators

  • Tommy's

    collaborator OTHER

  • University of Birmingham

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-02-28
Primary Completion
2020-09-11
Completion
2021-01-15

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03703401 on ClinicalTrials.gov