Influence of Opioid Analgesia on Circulating Tumor Cells in Open Colorectal Cancer Surgery
NCT03700411 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 125
Last updated 2023-12-07
Summary
To compare the effects of three types of perioperative analgesia on the number of circulating tumor cells following radical colorectal cancer surgery. To find correlations with other perioperative factors and clinical/pathological disease characteristics.
Conditions
- Colorectal Cancer
- Circulating Tumor Cell
Interventions
- DRUG
-
Morphine
Morphine intravenous
- DRUG
-
Piritramid
Piritramid intravenous
- DRUG
-
Epidural
Perioperative epidural analgesia
Sponsors & Collaborators
-
General University Hospital, Prague
collaborator OTHER -
Tomas Bata Hospital, Czech Republic
collaborator OTHER -
University Hospital Ostrava
collaborator OTHER -
Hospital Novy Jicin
collaborator UNKNOWN -
The Institute of Molecular and Translational Medicine, Czech Republic
lead OTHER
Principal Investigators
-
Marian Hajduch, MD PhD · Institute of Molecular and Translational Medicine, Palacky University, Olomouc
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-01-07
- Primary Completion
- 2023-11-01
- Completion
- 2023-12-06
Countries
- Czechia
Study Locations
More Related Trials
-
The Comparison of Postoperative Pain After Colon Resection in Intravenous Patient-controlled Analgesia Between Conventional Mode and Optimizing B.I Mode With 'PAINSTOP' Equipment
NCT03011359 ·Status: COMPLETED ·Phase: NA
-
Effect of General Anesthesia and Mechanical Ventilation on Plasma Metabolite in Patient With Colorectal Cancer Resection
NCT03137628 ·Status: UNKNOWN
-
Supervised Exercise for Post-surgery Colorectal Cancer Patients
NCT05090215 ·Status: COMPLETED ·Phase: NA
-
Antibiotic Prophylaxis in Rectal Cancer Surgery: Oral With Intravenous Versus Intravenous Antibiotics.
NCT03436719 ·Status: UNKNOWN ·Phase: NA
-
Sleep and Survival in Colorectal Cancer
NCT03254836 ·Status: UNKNOWN
-
Cardiopulmonary Exercise Test Data Averaging Methods and Preoperative Risk Assessment
NCT05353127 ·Status: COMPLETED
-
Observing the Perioperative Effects of Prehabilitation in Colorectal Cancer Patients
NCT04762914 ·Status: COMPLETED
-
Improvement of Fluid Balance in Patients Undergoing Surgery of the Colon and Rectum
NCT01175317 ·Status: COMPLETED ·Phase: PHASE4
-
CPET in Colorectal Surgery
NCT02298907 ·Status: COMPLETED
-
Local Anesthetic Wound Infusion and Functional Recovery After Colon Surgery
NCT01062919 ·Status: TERMINATED ·Phase: NA
-
Advanced Geriatric Evaluation and Quality of Life in Colorectal Cancer Surgery
NCT04443816 ·Status: COMPLETED
-
Prospective Randomised Trial of Exercise and / or Antioxidants in COlorectal Cancer Patients Undergoing Surgery.
NCT02264496 ·Status: COMPLETED ·Phase: NA
-
Colon Cancer Surgery in the Aged; Postoperative Outcome, Functional Recovery and Survival.
NCT03904121 ·Status: COMPLETED
-
Regional Anesthesia in Colon Rectal Surgery
NCT00684229 ·Status: WITHDRAWN ·Phase: NA
-
Effects of Postoperative Pain Management on Immune Function After Laparoscopic Resection of Colorectal Cancer
NCT02012244 ·Status: COMPLETED ·Phase: NA
-
Mechanical Bowel Preparation With or Without Oral Antibiotics for Colorectal Cancer Surgery
NCT03563586 ·Status: UNKNOWN ·Phase: NA
-
Inflammatory Response After Colorectal Cancer Surgery
NCT01427647 ·Status: COMPLETED ·Phase: NA
-
Trial of Antibiotic Prophylaxis in Elective Colorectal Surgery
NCT00292708 ·Status: COMPLETED ·Phase: PHASE3
-
Short-term Outcomes of Full Bowel Preparation (MBP+OA) for Colon Cancer Resections Versus no Bowel Preparation
NCT05546892 ·Status: UNKNOWN ·Phase: NA
-
Assessment of Quality of Life and Social Support Gained in Patients Before and After Colorectal Cancer Surgery
NCT06395766 ·Status: RECRUITING
-
Optimization of Patients' Physical and Mental Status Prior to Colorectal Cancer Surgery
NCT04909567 ·Status: UNKNOWN ·Phase: NA
-
Effect of Intrathecal Morphine on Quality of Recovery After Laparoscopic Colorectal Cancer Surgery
NCT06636864 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
General Anesthesia Combined With Epidural Anesthesia Mitigates the Surgical Stress-related Immunosuppression in Patients With Colorectal Cancer
NCT01978717 ·Status: COMPLETED ·Phase: NA
-
Immunological and Oxidative Stress Response in Relation to Abdominal Cancer Surgery
NCT03473327 ·Status: COMPLETED
-
Perioperative Use of a Selective COX2 Inhibitor in Patients Undergoing Elective Colorectal Surgery: the Effect on Post-operative Bowel Motility and Post-operative Pain
NCT02790203 ·Status: UNKNOWN ·Phase: NA