A Study of LY3451838 in Healthy Participants

NCT03692949 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 53

Last updated 2025-09-11

Study results available
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Summary

The study has two parts. In Part A, single increasing doses of LY3451838 will be administered intravenously (into a vein). In Part B, a single dose of LY3451838 will be administered subcutaneously (just under the skin).

Conditions

  • Healthy

Interventions

DRUG

LY3451838

Administered IV Part A

DRUG

LY3451838

Administered IV Part A

DRUG

LY3451838

Administered IV Part A

DRUG

LY3451838

Administered IV Part A

DRUG

LY3451838

Administered IV Part A

DRUG

LY3451838

Administered IV Part A

DRUG

LY3451838

Administered SC Part B

DRUG

Placebo

Administered IV in Part A and SC in Part B

Sponsors & Collaborators

Principal Investigators

  • Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST) · Eli Lilly and Company

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-12-11
Primary Completion
2020-02-26
Completion
2020-02-26

Countries

  • Singapore

Study Locations

More Related Trials

Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03692949 on ClinicalTrials.gov