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The Changes of Retinal Capillaries After Half-dose PDT Measured by OCTA in Eyes With CSC

NCT03692169 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2018-10-02

No results posted yet for this study

Summary

To determine changes in retinal and choroidal capillaries with optical coherence tomographic angiography (OCTA) after half-dose photodynamic therapy (hd-PDT) in eyes with central serous chorioretinopathy (CSC).

Conditions

  • Central Serous Chorioretinopathy

Interventions

PROCEDURE

Half-dose photodynamic therapy

Half-dose photodynamic therapy was achieved by administering 3mg/m² of Verteporfin (Visudyne; Novartis, Switzerland) intravenously over a period of 10 minutes. Fifteen minutes after commencing the verteporfin infusion the greatest linear dimension was exposed to a 689 nm laser light with a florescence of 600 mw/cm² for 83 seconds and a total energy of 50 J/cm². Optical coherence tomography angiography (OCTA) with the split-spectrum amplitude-decorrelation angiography algorithm (XR Optovue, Fremont, CA, USA) and spectral domain OCT (SD-OCT) were performed at baseline and each follow-up (one month and three months) visit after hd-PDT.

Sponsors & Collaborators

  • Jin Chen-jin

    lead OTHER

Principal Investigators

  • Chenjin Jin · Zhongshan Ophthalmic Center, Sun Yat-sen University

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-10-31
Primary Completion
2018-10-10
Completion
2019-06-30
FDA Device
Yes

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03692169 on ClinicalTrials.gov