Potential of Circulating Tumor DNA to Assess the Tumor Response to Neoadjuvant Chemotherapy in Breast Cancer Patients
NCT03688035 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2018-09-27
Summary
Breast cancer is the most common malignant tumor in women worldwide,and there exist a large part of patients need to receive neoadjuvant chemotherapy(NAC) before the curative surgery.Circulating tumor DNA(ctDNA) is the circulating free DNA in the blood that originates from cancers,and it can be detected by modern technologies in plasma.In this prospective study,investigators aim to observe the correlation between tumor response to neoadjuvant chemotherapy and ctDNA.
Conditions
- Breast Cancer
- Neoadjuvant Chemotherapy
- Circulating Tumor DNA
Sponsors & Collaborators
-
Zhiyong Yu
lead OTHER
Principal Investigators
-
Zhiyong Yu, PHD · Shandong Cancer Hospital and Institute
-
Zhaoyun Liu, MD · Shandong Cancer Hospital and Institute
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-09-20
- Primary Completion
- 2019-09-20
- Completion
- 2019-09-20
Countries
- China
Study Locations
More Related Trials
-
Clinical Application of CTDNA in Operable Breast Cancer Patients
NCT02797652 ·Status: UNKNOWN
-
Evaluation of Treatment Efficacy by Circulating Tumor Cell Phenotype Surveillance in Breast Cancer Patients
NCT05326295 ·Status: RECRUITING
-
Circulating Tumor DNA (ctDNA)-Guided Late-Line Treatment in Patients With Late-Stage Breast Cancer
NCT05427617 ·Status: COMPLETED
-
Detecting Circulating Tumor Cells (CTCs) and Cell Free DNA (cfDNA) in Peripheral Blood of Breast Cancer (BC) Patients to Develop the Clinical Application for Early Detection and Diagnostics
NCT03511859 ·Status: UNKNOWN
-
Clinical Application of ctDNA in Early Screening of Breast Cancer
NCT03973034 ·Status: UNKNOWN
-
Clinical Application of ctDNA Dynamic Monitoring in Neoadjuvant Therapy for HER2-positive Breast Cancer Patients
NCT06479460 ·Status: RECRUITING
-
Circulating Tumor DNA to Guide Changes in Standard of Care Chemotherapy
NCT05770531 ·Status: RECRUITING ·Phase: PHASE2
-
ctDNA Monitoring in Early Breast Cancer
NCT04353557 ·Status: RECRUITING
-
Clinical Application of Circulating Tumor DNA (ctDNA) in Patients With Late-stage Breast Cancer
NCT05079074 ·Status: COMPLETED
-
Pre-analytical Factors Affecting ctDNA Analysis in Early and Locally Advanced Breast Cancer
NCT05945290 ·Status: COMPLETED
-
Circulating Tumor DNA and Immunophenotyping as Potential Biomarkers With Regional Nodal Irradiation for Breast Cancer
NCT04308720 ·Status: ACTIVE_NOT_RECRUITING
-
Correlation Between Molecular Typing and Neoadjuvant Chemotherapy in Breast Cancer Patients Based on Mammaprint/Blueprint Test
NCT04264468 ·Status: UNKNOWN
-
Study on Early Auxiliary Diagnosis and Postoperative Recurrence Monitoring of Breast Cancer
NCT05858242 ·Status: RECRUITING
-
Circulating Tumor Cells Screen for Breast Cancer
NCT05633680 ·Status: UNKNOWN
-
Discerning the Impact of ctDNA Detection on Patient Decision Making in Early Stage Breast Cancer: a Conjoint Analysis
NCT05730010 ·Status: COMPLETED
-
The Study on the Clinical Utility of Liquid Biopsy in Breast Cancer
NCT02902991 ·Status: UNKNOWN
-
Monitoring Plasma Tumor DNA in Early-Stage Breast Cancer
NCT02743910 ·Status: ACTIVE_NOT_RECRUITING
-
Genomic Markers for Measuring Breast Cancer Response to Neoadjuvant Chemotherapy
NCT03709134 ·Status: COMPLETED
-
Diagnostic Biomarkers Exploration of Breast Cancer From Serum and Urine
NCT06102018 ·Status: RECRUITING
-
Genomic Signatures to Predict Treatment Response
NCT02032745 ·Status: COMPLETED
-
Prophylactic Irradiation to the Contralateral Breast for BCAs Patients
NCT04960839 ·Status: RECRUITING ·Phase: NA
-
Clinical Value of Next Generation Sequencing in Endocrine Therapy for Advanced Hormone Receptor Positive/HER-2 Negative Breast Cancer
NCT03786575 ·Status: UNKNOWN ·Phase: NA
-
Circulating Tumor Cell Detection in Patients With Luminal A Breast Cancer
NCT04065321 ·Status: RECRUITING
-
Analysis of Circulating Tumor DNA (ctDNA) in HER2-low Advanced/Metastatic Breast Cancer
NCT06706557 ·Status: RECRUITING
-
Prognosis and Targeted Therapy Related Molecular Screening Program for Patients of Breast Cancer in China
NCT03792529 ·Status: UNKNOWN