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NAC for Head Trauma-induced Anosmia

NCT03680911 · Status: TERMINATED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 7

Last updated 2021-02-04

Study results available
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Summary

This study will compare administration of N-Acetyl Cysteine (NAC) versus placebo for the treatment of olfactory loss due to head injury. The hypothesis is that treatment with NAC acutely after head injury will result in improved olfactory function

Conditions

  • Anosmia
  • Head Trauma

Interventions

DRUG

N Acetyl Cysteine

2 g PO BID for 4 days, then 1.5 g PO BID for 2 days

DRUG

Placebo oral capsule

2 g PO BID for 4 days, then 1.5 g PO BID for 2 days

Sponsors & Collaborators

  • University of Miami

    lead OTHER

Principal Investigators

  • Roy Casiano, MD · University of Miami

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-10-12
Primary Completion
2020-01-07
Completion
2020-01-07
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03680911 on ClinicalTrials.gov