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Utility of Perfusion MRI to Detect Radiation Necrosis in Patients With Brain Metastases

NCT03680144 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 8

Last updated 2026-04-24

No results posted yet for this study

Summary

This trial studies how well dynamic susceptibility contrast-magnetic resonance imaging (MRI) works in determining radiation necrosis and tumor progression in participants with cancer that has spread to the brain and are being treated with radiation therapy. Diagnostic procedures, such as dynamic susceptibility contrast-MRI, may improve the ability to determine indeterminate post-treatment changes seen on imaging after radiation therapy.

Conditions

  • Invasive Malignant Neoplasm
  • Metastatic Malignant Neoplasm in the Brain

Interventions

PROCEDURE

Dynamic Susceptibility Contrast-MRI (DSC-MRI)

Undergo DSC-MRI

PROCEDURE

Magnetic Resonance Imaging (MRI)

Undergo diagnostic MRI

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH

  • National Institutes of Health (NIH)

    collaborator NIH

  • Emory University

    lead OTHER

Principal Investigators

  • Hui-Kuo Shu, MD, PhD · Emory University

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-11-28
Primary Completion
2020-11-05
Completion
2021-06-15

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03680144 on ClinicalTrials.gov