Dendritic Cell/AML Fusion Cell Vaccine Following Allogeneic Transplantation in AML Patients
NCT03679650 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 28
Last updated 2026-05-12
Summary
This research study is studying a cancer vaccine called Dendritic Cell/AML Fusion vaccine (DC/AML vaccine) as a possible treatment for Acute Myelogenous Leukemia (AML).
The interventions involved in this study are:
* Dendritic Cell/AML Fusion vaccine (DC/AML vaccine)
* Decitabine, a chemotherapy drug
Conditions
- Acute Myelogenous Leukemia
Interventions
- BIOLOGICAL
-
DC/AML fusion cells
An investigational agent that tries to help the immune system to recognize and fight against cancer cells
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH - collaborator OTHER
-
Beth Israel Deaconess Medical Center
lead OTHER
Principal Investigators
-
Jacalyn Rosenblatt, MD · Beth Israel Deaconess Medical Center
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-10-11
- Primary Completion
- 2026-03-31
- Completion
- 2026-08-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
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