A Multi-center Trial to Establish a Model for the Early Diagnosis of Colorectal Cancer by the Detection of 5-hydroxymethylcytosine (5-hmC) in Plasma Cell-free DNA
NCT03676075 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1500
Last updated 2018-09-18
Summary
In this study, the investigators establish a model for the early diagnosis of colorectal cancer based on the detection of 5-hydroxymethylcytosine (5-hmC) in training group and validate the effectiveness of the model using a validation group recruited from multiple centers.
Conditions
- Colorectal Cancer
- Adenoma
Sponsors & Collaborators
-
Fudan University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-12-01
- Primary Completion
- 2019-06-30
- Completion
- 2019-06-30
Countries
- China
Study Locations
More Related Trials
-
An Exploratory Study on Gene Methylation Detection of Colorectal Cancer
NCT07033156 ·Status: RECRUITING
-
Multiple Screening Methods for the Detection of Chinese Colorectal Advanced Adenomatous Polyps and Cancer
NCT03411707 ·Status: UNKNOWN
-
Diagnostic Accuracy of a Panel of Bacterial Gene Markers (M3) for Colorectal Advanced Neoplasia
NCT05405673 ·Status: RECRUITING
-
Treatment Response Prediction System of mCRC Patients Based on CTC
NCT04917276 ·Status: NOT_YET_RECRUITING
-
Early Screening of Colorectal Cancer Based on Plasma Multi-omics Combining With Artificial Intelligence
NCT05587452 ·Status: UNKNOWN
-
Evaluation of a Point-of-care Testing Instrument for Fecal Immunochemical Test
NCT05232721 ·Status: UNKNOWN
-
Clinical Validation of Stool DNA-based SDC2 Methylation Test for Colorectal Cancer Detection
NCT03146520 ·Status: COMPLETED
-
Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas
NCT00843375 ·Status: RECRUITING
-
Blood and Stool Sample Collection in Subjects With a Diagnosis of Colorectal Cancer or Colorectal Lesion: Act Fast
NCT03789162 ·Status: COMPLETED
-
Multi-marker Stool Test for Detection of Colorectal Neoplasia: Marker Panel Selection and Technical Development Studies
NCT01260168 ·Status: COMPLETED
-
Fecal Immunochemical Test for Advanced Adenoma Detection in Colorectal Cancer Screening
NCT05200611 ·Status: UNKNOWN
-
Colorectal Cancer Screening Using Stool DNA-based SDC2 and SFRP2 Methylation Test in China
NCT04515082 ·Status: UNKNOWN
-
Stool-based SDC2 DNA Methylation Test for the Detection of Colorectal Advanced Adenomatous Polyps and Cancer
NCT04221854 ·Status: UNKNOWN ·Phase: NA
-
Fecal DNA Methylation Test for Colorectal Cancer Screening
NCT04823793 ·Status: UNKNOWN
-
Colon Cancer Study of Fecal Samples in Shanghai, China
NCT01778595 ·Status: COMPLETED
-
Multitarget Stool FIT-DNA Study for Colorectal Cancer Early Screening in China
NCT04287335 ·Status: COMPLETED
-
A Comparison of Different Fecal Occult Blood Test for Colorectal Cancer Screening
NCT04454099 ·Status: COMPLETED
-
Prognosis Predicting of CRC Patients Based on Morphology and Molecular Biomaker of CTC
NCT04912882 ·Status: NOT_YET_RECRUITING
-
Next-generation Sequencing of Colorectal Cancer Somatic Cells to Guide Genetic Susceptibility Gene Mutations Screening.
NCT04280666 ·Status: UNKNOWN
-
Validation of a Molecular Signature for Early Detection of Colorectal Cancer
NCT06738511 ·Status: COMPLETED ·Phase: NA
-
A Prospective Cohort Study on Colorectal Cancer Screening in Community Population
NCT05485077 ·Status: RECRUITING
-
Circulating Tumor DNA Methylation Guided Postoperative Follow-up Strategy for Non-metastatic Colorectal Cancer
NCT05904665 ·Status: RECRUITING ·Phase: NA
-
Risk of Metachronous Advanced Colorectal Neoplastic Among Individuals With Varying Numbers of Non-Advanced Adenomas Detected During Screening Colonoscopy
NCT07302139 ·Status: COMPLETED
-
Plasma-based Colorectal Cancer Screening Research & Development
NCT04027790 ·Status: COMPLETED
-
Establishment and Clinical Validation of New Technologies for Accurate Screening of Colorectal Cancer Based on Multi-omics
NCT04913233 ·Status: UNKNOWN