Trial Outcomes & Findings for INVSENSOR00027 Clinical Performance Study (NCT NCT03650192)

NCT ID: NCT03650192

Last Updated: 2021-01-29

Results Overview

For each subject's position detection, INVSENSOR00027 output will be compared against observer's notes at each turn of the subject. Correctly detected position changes will be marked as True Positive. Missed detections (if any) will be counted. The sensitivity of INVSENSOR00027's posture change detection will be computed as Sensitivity = True Positive/(True Positive+Missed Detection)

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

40 participants

Primary outcome timeframe

1-5 hours

Results posted on

2021-01-29

Participant Flow

Participant milestones

Participant milestones
Measure
INVSENSOR00027 Test Group
The subjects will be enrolled into the test group and will receive the INVSENSOR00027 investigational sensor. INVSENSOR00027: Investigational, noninvasive sensor that will be placed on the subject's chest and/or back. INVSENSOR00027 measures signals regarding subject's movement and posture, heart rate, and respiratory rate.
Overall Study
STARTED
40
Overall Study
COMPLETED
40
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

INVSENSOR00027 Clinical Performance Study

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
INVSENSOR00027 Test Group
n=40 Participants
The subjects will be enrolled into the test group and will receive the INVSENSOR00027 investigational sensor. INVSENSOR00027: Investigational, noninvasive sensor that will be placed on the subject's chest and/or back. INVSENSOR00027 measures signals regarding subject's movement and posture, heart rate, and respiratory rate.
Age, Categorical
<=18 years
0 Participants
n=99 Participants
Age, Categorical
Between 18 and 65 years
38 Participants
n=99 Participants
Age, Categorical
>=65 years
2 Participants
n=99 Participants
Sex: Female, Male
Female
22 Participants
n=99 Participants
Sex: Female, Male
Male
18 Participants
n=99 Participants
Race/Ethnicity, Customized
African American
11 Participants
n=99 Participants
Race/Ethnicity, Customized
Asian or Pacific Islander
4 Participants
n=99 Participants
Race/Ethnicity, Customized
Caucasian
18 Participants
n=99 Participants
Race/Ethnicity, Customized
Hispanic
4 Participants
n=99 Participants
Race/Ethnicity, Customized
Native American
1 Participants
n=99 Participants
Race/Ethnicity, Customized
Other
2 Participants
n=99 Participants
Region of Enrollment
United States
40 participants
n=99 Participants

PRIMARY outcome

Timeframe: 1-5 hours

For each subject's position detection, INVSENSOR00027 output will be compared against observer's notes at each turn of the subject. Correctly detected position changes will be marked as True Positive. Missed detections (if any) will be counted. The sensitivity of INVSENSOR00027's posture change detection will be computed as Sensitivity = True Positive/(True Positive+Missed Detection)

Outcome measures

Outcome measures
Measure
INVSENSOR00027 Test Group
n=40 Participants
The subjects will be enrolled into the test group and will receive the INVSENSOR00027 investigational sensor. INVSENSOR00027: Investigational, noninvasive sensor that will be placed on the subject's chest and/or back. INVSENSOR00027 measures signals regarding subject's movement and posture, heart rate, and respiratory rate.
Sensitivity of INVSENSOR00027's Posture Change Detection
100 percent sensitivity for posture change

PRIMARY outcome

Timeframe: 1-5 hours

For each subject's activity (e.g., walking and upright) detection, INVSENSOR00027 output will be compared against observer's notes. Correctly detected activity changes will be marked as True Positive. Missed detections (if any) will be counted. The sensitivity of INVSENSOR00027's activity change detection will be computed as Sensitivity = True Positive/(True Positive+Missed Detection).

Outcome measures

Outcome measures
Measure
INVSENSOR00027 Test Group
n=40 Participants
The subjects will be enrolled into the test group and will receive the INVSENSOR00027 investigational sensor. INVSENSOR00027: Investigational, noninvasive sensor that will be placed on the subject's chest and/or back. INVSENSOR00027 measures signals regarding subject's movement and posture, heart rate, and respiratory rate.
Sensitivity of INVSENSOR00027's Activity Change Detection
96.7 percent sensitivity for posture change

PRIMARY outcome

Timeframe: 1-5 hours

Population: Fall detection was an optional event per protocol.

Outcome measures

Outcome measures
Measure
INVSENSOR00027 Test Group
n=3 Participants
The subjects will be enrolled into the test group and will receive the INVSENSOR00027 investigational sensor. INVSENSOR00027: Investigational, noninvasive sensor that will be placed on the subject's chest and/or back. INVSENSOR00027 measures signals regarding subject's movement and posture, heart rate, and respiratory rate.
Sensitivity of INVSENSOR00027's Fall Event Detection
100 percent sensitivity for fall detection

SECONDARY outcome

Timeframe: 1-5 hours

Population: 2 subjects were excluded due to data collection issues.

Accuracy will be determined by comparing the respiratory rate measurement of the INVSENSOR00027 to the respiratory rate reference (RRef) and calculating the arithmetic root mean square (Arms) value. In order to obtain the Arms value, the RR measurement from the reference is subtracted from the INVSENSOR00027 RR measurement for a number of samples. The average of this difference is computed as the bias. The standard deviation of the differences is computed as the precision. The square root of the sum of the squares of bias and precision is computed as the Arms value.

Outcome measures

Outcome measures
Measure
INVSENSOR00027 Test Group
n=38 Participants
The subjects will be enrolled into the test group and will receive the INVSENSOR00027 investigational sensor. INVSENSOR00027: Investigational, noninvasive sensor that will be placed on the subject's chest and/or back. INVSENSOR00027 measures signals regarding subject's movement and posture, heart rate, and respiratory rate.
Respiratory Rate Detection
1.7 A(RMS) of breaths per minute

Adverse Events

INVSENSOR00027 Test Group

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Ahmed Alghazi

Masimo

Phone: 949-297-7000

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place