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Pain in Parkinson's Disease With Motor Fluctuations.

NCT03648671 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 48

Last updated 2018-08-27

No results posted yet for this study

Summary

Pain (spontaneous pain) is a fundamental non-motor symptom (NMS) of Parkinson's disease (PD) that is prevalent throughout the condition and often unrecognized and undertreated. The study of the scalp laser-evoked potentials (LEPs) (evoked pain) allows a non-invasive exploration of pain central pathways in humans. This technique proved useful in elucidating the physiopathology underlying different pain syndromes. This study has been conceived to study spontaneous pain (and/or evoked pain by laser stimulation) in PD patients (with or without pain) with motor fluctuations under drugs-on (Safinamide Metansolfonato or Rasagilina Mesilato).

Conditions

  • Parkinson Disease

Interventions

DRUG

safinamide metansolfonato (12 weeks)

safinamide metansolfonato

DRUG

safinamide metansolfonato (12 weeks)

safinamide metansolfonato

DRUG

rasagilina mesilato (12 weeks)

rasagilina mesilato

DRUG

rasagilina mesilato (12 weeks)

rasagilina mesilato

Sponsors & Collaborators

  • Azienda Ospedaliera Universitaria Integrata Verona

    collaborator OTHER

  • Universita di Verona

    lead OTHER

Principal Investigators

  • Michele Tinazzi, MD, PhD · Azienda Ospedaliera Universitaria Integrata Verona

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-03-28
Primary Completion
2019-03-28
Completion
2019-11-30

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03648671 on ClinicalTrials.gov