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Cognitive Control of Negative Stimuli in BPD

NCT03636139 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2024-02-22

No results posted yet for this study

Summary

Borderline personality disorder (BPD) is characterized by impairments in the cognitive control of negative information. These impairments in cognitive control are presumably due to blunted activity of the dorsolateral prefrontal cortex (dlPFC) along with enhanced activations of the limbic system. However, the impact of an excitatory stimulation of the dlPFC still needs to be elucidated. In the present study, we therefore assigned 50 patients with BPD and 50 healthy controls to receive either anodal or sham stimulation of the right dlPFC in a double-blind, randomized, between-subjects design.

Conditions

  • Borderline Personality Disorder

Interventions

DEVICE

transcranial DC stimulation : anodal

anodal stimulation of the right dlPFC (i.e. F4) for 20 minutes

DEVICE

transcranial DC stimulation : sham

sham stimulation of the right dlPFC (i.e. F4) for 20 minutes

Sponsors & Collaborators

  • Freie Universität Berlin

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-01-31
Primary Completion
2017-06-30
Completion
2017-06-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03636139 on ClinicalTrials.gov