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Generation of Thrombin and Prediction of Deep Vein Thrombosis Post Prosthetic Orthopedic Surgery of the Lower Limbs

NCT03634124 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 146

Last updated 2026-02-11

No results posted yet for this study

Summary

The numerical ratio between the value of the thrombin generation test performed without soluble thrombomodulin and the value of the thrombin generation test performed in the presence of soluble thrombomodulin, performed pre-surgically, could predict the risk of early venous thromboembolism after placement of total hip or knee prosthesis.

Conditions

  • Deep Vein Thrombosis
  • Total Hip Prosthesis
  • Knee Prosthesis

Interventions

BIOLOGICAL

Blood test

Additional blood test of 4,5 ml of venous blood

OTHER

Doppler ultrasound

Vascular ultrasonic vascular exploration of the lower limbs

Sponsors & Collaborators

  • Centre Hospitalier Universitaire de Nīmes

    lead OTHER

Principal Investigators

  • Eva Cochery-Nouvellon, Dr · Centre Hospitalier Universitaire de Nīmes

Study Design

Allocation
NA
Purpose
OTHER
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-02-21
Primary Completion
2023-02-20
Completion
2023-10-17

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03634124 on ClinicalTrials.gov