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Magnesium and Vascular Stiffness

NCT03632590 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 162

Last updated 2018-08-15

No results posted yet for this study

Summary

This four-arm randomized controlled trial was designed to study the effects of magnesium supplements (total daily dose: 450 mg elemental magnesium) on vascular stiffness in healthy overweight and slightly obese men and women. In addition, the effects of magnesium supplements on blood pressure and gut microbiota will be evaluated. Three groups will receive magnesium supplements (magnesium oxide, magnesium citrate or magnesium sulphate) and one group will receive a placebo.

Conditions

  • Vascular Stiffness
  • Blood Pressure

Interventions

DIETARY_SUPPLEMENT

Magnesium Citrate

450 mg of Magnesium Citrate per day (6 capsules per day) for 24 weeks

DIETARY_SUPPLEMENT

Magnesium Sulfate

450 mg of Magnesium Sulfate per day (6 capsules per day) for 24 weeks

DIETARY_SUPPLEMENT

Magnesium Oxide

450 mg of Magnesium Oxide per day (6 capsules per day) for 24 weeks

DRUG

Placebo

The placebo capsules will contain starch (Amylum solani) for 24 weeks

Sponsors & Collaborators

  • Nedmag Industries Mining and Manufacturing B.V.

    collaborator UNKNOWN

  • University Medical Center Groningen

    lead OTHER

Principal Investigators

  • Stephan JL Bakker, MD-PhD · University Medical Center Groningen

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
45 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-03-27
Primary Completion
2020-01-31
Completion
2020-01-31

Countries

  • Netherlands

Study Locations

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Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03632590 on ClinicalTrials.gov