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Early Detection of Anastomotic Leakage by Microdialysis Catheters

NCT03627559 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 35

Last updated 2018-08-13

No results posted yet for this study

Summary

Anastomotic leakage of the pancreatojejunostomy is often discovered with considerable delay, causing severe peritonitis, hemorrhage due to erosion of vessels, sepsis, and death. Microdialysis catheters can detect focal inflammation and ischemia, and has a potential for early detection of anastomotic leakage. This observational study will examine if monitoring with microdialysis catheters can detect anastomotic leakage after pancreaticoduodenectomy earlier than current standard of care.

Conditions

  • Pancreatic Cancer
  • Pancreaticoduodenal; Fistula
  • Pancreas; Fistula
  • Pancreatic Fistula

Interventions

PROCEDURE

Pancreaticoduodenectomy microdialysis catheter analyses

A thin microdialysis catheter is implanted before skin closure after pancreaticoduodenectomy. Analyses of the microdialysate are done at certain timepoints postoperatively. No intervention is done based on the results. The patients are following standard of care.

Sponsors & Collaborators

  • Oslo University Hospital

    lead OTHER

Principal Investigators

  • Espen Lindholm, ph.d · Oslo University Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-10-01
Primary Completion
2014-03-31
Completion
2018-07-01

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Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03627559 on ClinicalTrials.gov