MedTrace Logo

Potency of Topical Corticosteroids in Combination Preparations

NCT03606954 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2018-07-31

No results posted yet for this study

Summary

Several combination topical drugs are available on the market. The potency of corticosteroids depends on a particular molecular structure and the skin penetration properties. Besides molecular structure, a penetration of a corticosteroid molecule correlates with physical properties of the vehicle which depend on physical properties of the vehicle constituents.

Vasoconstriction assay is considered as the gold standard for testing potency of topical corticosteroids.

Conditions

  • Skin Toxicity

Interventions

COMBINATION_PRODUCT

Combination topical corticosteroid

Comparison of a vasoconstriction index between the 2 study arms

Sponsors & Collaborators

  • Soroka University Medical Center

    collaborator OTHER

  • Ben-Gurion University of the Negev

    lead OTHER

Principal Investigators

  • Raed Khoury, MD · Soroka University Medical Center & Ben Gurion University

Study Design

Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-11-30
Primary Completion
2019-03-31
Completion
2019-04-30

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03606954 on ClinicalTrials.gov