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Epi Off Versus Epi on Corneal Collagen Cross-linking in Keratoconus Patients

NCT03598634 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32

Last updated 2018-07-26

No results posted yet for this study

Summary

To evaluate two different techniques of cross linking: standard epithelium off (CXL epi off) versus trans-epithelial (CXL epi on) cross linking in patient with progressive keratoconus.

Conditions

  • Keratoconus

Interventions

PROCEDURE

administration of riboflavin for epi-off cross-linking

riboflavin 0.1% in 20% dextran solution

PROCEDURE

administration of riboflavin for epi-on cross-linking

riboflavin 0.1% in 15% dextran solution supplemented with tris-hydroxymethylaminomethane and sodium ethylenediminetetraacetic acid

Sponsors & Collaborators

  • University of Molise

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-06-01
Primary Completion
2015-06-30
Completion
2017-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03598634 on ClinicalTrials.gov