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TREatment With Beta-blockers After myOcardial Infarction withOut Reduced Ejection fracTion"

NCT03596385 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 8505

Last updated 2025-06-06

No results posted yet for this study

Summary

REBOOT clinical trial will study whether long-term maintenance beta-blockers therapy results in a clinical benefit after heart attack without reduced left ventricular function. Half of the participants will be randomized to receive long-term beta-blocker therapy and the other half to no beta-blocker therapy after hospital discharge. All patients will be followed up for up to 5 years to determine the occurrence of adverse events (all cause mortality, re-infarction, and heart failure admission).

Conditions

Interventions

DRUG

Beta blocker

long-term maintenance beta-blocker therapy

Sponsors & Collaborators

  • Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III

    lead OTHER

Principal Investigators

  • Borja Ibañez, MD PhD FESC · CNIC

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-10-31
Primary Completion
2025-01-31
Completion
2025-01-31

Countries

  • Italy
  • Spain

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03596385 on ClinicalTrials.gov