Characterization of T-Cell Response in Participants Previously Treated With JNJ-54861911 (Atabecestat)
NCT03587376 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 9
Last updated 2025-04-27
Summary
The purpose of this study is to determine T-cell mediated inflammatory immune response in some participants previously exposed to atabecestat.
Conditions
- Alzheimer Disease
Interventions
- DRUG
-
Atabecestat
Blood samples will be collected from participants previously treated with atabecestat.
Sponsors & Collaborators
-
Janssen Research & Development, LLC
lead INDUSTRY
Principal Investigators
-
Janssen Research & Development, LLC Clinical Trial · Janssen Research & Development, LLC
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- OTHER
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 50 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-05-30
- Primary Completion
- 2018-08-23
- Completion
- 2018-08-23
Countries
- Belgium
- France
- Germany
- Spain
- Sweden
Study Locations
More Related Trials
-
A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease
NCT05531656 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study to Evaluate the Safety and Efficacy of CT1812 in Subjects With Mild to Moderate Alzheimer's Disease.
NCT03507790 ·Status: COMPLETED ·Phase: PHASE2
-
Safety, Tolerability and the Effects on Cerebrospinal Fluid Spectrin Breakdown Product-145 Levels of ABT-957 in Subjects With Mild Alzheimer's Disease and Mild Cognitive Impairment
NCT02573740 ·Status: TERMINATED ·Phase: PHASE1
-
Study Evaluating Safety, Tolerability, And Immunogenicity Of ACC-001 In Subjects With Mild To Moderate Alzheimer's Disease
NCT00479557 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Evaluate Dietary Supplementation With a Version of Anatabloc(R) in Subjects With Alzheimer's Disease
NCT01669876 ·Status: TERMINATED ·Phase: PHASE2
-
Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD) Study
NCT04685590 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Long Term Extension Study Evaluating Safety, Tolerability And Immunogenicity Of ACC-001 In Japanese Subjects With Mild To Moderate Alzheimer's Disease
NCT01238991 ·Status: TERMINATED ·Phase: PHASE2
-
TNF-Alpha Inhibition for Treatment of Alzheimer's Disease
NCT00203320 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate the Safety, Tolerability and Pharmacokinetics of JNJ-54861911 in Healthy Volunteers Compared With Placebo
NCT01827982 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Tolerability Study in Patients With Mild to Moderate Alzheimer's Disease (AD)
NCT00411580 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
NCT07169578 ·Status: RECRUITING ·Phase: PHASE3
-
Low Dose IL2 Immunotherapy in AD
NCT05821153 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Semorinemab in Patients With Moderate Alzheimer's Disease
NCT03828747 ·Status: COMPLETED ·Phase: PHASE2
-
Study With Lu AF20513 in Patients With Mild Alzheimer's Disease (AD) or Mild Cognitive Impairment (MCI) Due to AD
NCT03819699 ·Status: TERMINATED ·Phase: PHASE1
-
Efficacy and Safety of Memantine in Moderate to Severe Alzheimer's Disease
NCT00857649 ·Status: TERMINATED ·Phase: PHASE3
-
Study to Evaluate the Efficacy and Safety of GSK239512 in Alzheimer's Disease
NCT01009255 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical- and Immunological Activity, Safety and Tolerability of Different Doses / Formulations of AFFITOPE AD02 in Early Alzheimer's Disease
NCT01117818 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild to Moderate Alzheimer's Disease
NCT01689246 ·Status: COMPLETED ·Phase: PHASE3
-
Pilot Study to Investigate the Safety and Feasibility of AntiRetroviral Therapy for Alzheimer's Disease
NCT04552795 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Safety, Tolerability and Abeta-specific Antibody Response of Repeated i.m. Injections of Adjuvanted CAD106 in Mild Alzheimer Patients
NCT01097096 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluate the Safety and Efficacy of AD-35 Tablet in Subjects With Mild to Moderate Alzheimer's Disease
NCT03790982 ·Status: UNKNOWN ·Phase: PHASE2
-
Clinical Trial of CT1812 in Mild to Moderate Alzheimer's Disease
NCT02907567 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Magnetic Resonance Spectroscopy Study of Memantine in Alzheimer's Disease
NCT00551161 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate the Impact of MABT5102A on Brain Amyloid Load and Related Biomarkers in Patients With Mild to Moderate Alzheimer's Disease
NCT01397578 ·Status: COMPLETED ·Phase: PHASE2
-
An Extension Study to Evaluate the Long-Term Safety and Tolerability of JNJ-54861911 in Participants in the Early Alzheimer's Disease Spectrum
NCT02406027 ·Status: TERMINATED ·Phase: PHASE2