A Clinical Trial of Decitabine in Relapse and Refractory Diffuse Large B Cell Lymphoma
NCT03579082 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2018-09-14
Summary
To explore the safety, tolerability and clinical effects of decitabine combined with R±DHAP for patients with replase and refractory Diffuse Large B cell lymphoma.
Conditions
Interventions
- DRUG
-
Decitabine
Given ivgtt
Sponsors & Collaborators
-
Mingzhi Zhang
lead OTHER
Principal Investigators
-
Mingzhi Zhang · The first affilliated hospital of zhengzhou university
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 14 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-06-01
- Primary Completion
- 2019-06-01
- Completion
- 2019-12-01
- FDA Drug
- Yes
Countries
- China
Study Locations
More Related Trials
-
Combination Chemotherapy and Rituximab in Treating Patients With Diffuse Large B-Cell Non-Hodgkin Lymphoma
NCT00974792 ·Status: UNKNOWN ·Phase: PHASE2
-
Safety and Efficacy Evaluation of Decitabine With R-GDP
NCT03535753 ·Status: UNKNOWN ·Phase: PHASE1
-
Study of Tisagenlecleucel in Combination With Pembrolizumab in r/r Diffuse Large B-cell Lymphoma Patients
NCT03630159 ·Status: COMPLETED ·Phase: PHASE1
-
Decitabine in Treating Patients With Advanced Refractory Solid Tumors or Lymphomas
NCT00089089 ·Status: TERMINATED ·Phase: PHASE1
-
p53/p16-Independent Epigenetic Therapy With Oral Decitabine/Tetrahydrouridine for Refractory/Relapsed Lymphoid Malignancies
NCT02846935 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Study of F527 in Patients With Relapsed or Refractory Lymphoma
NCT05293028 ·Status: UNKNOWN ·Phase: PHASE1
-
Phase II Study With Ga101-DHAP as Induction Therapy in Relapsed/Refractory DLBCL Patients
NCT02374424 ·Status: TERMINATED ·Phase: PHASE2
-
Clinical Study on the Safety and Efficacy of CD20/CD19 Cell Injection in the Treatment of Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
NCT07345741 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Lenalidomide, Rituximab, Gemcitabine, Oxaliplatin and Dexamethasone in Relapse and Refractory DLBCL
NCT03795571 ·Status: UNKNOWN ·Phase: PHASE1
-
Addition of Chidamide to the Combination Treatment of Decitabine Plus Camrelizumab in Combination Treatment Resistant/Relapsed Patients With Classical Hodgkin Lymphoma
NCT04233294 ·Status: RECRUITING ·Phase: PHASE2
-
Decitabine With or Without Valproic Acid in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
NCT00109824 ·Status: COMPLETED ·Phase: PHASE1
-
AZD1152 in Diffuse Large B-cell Lymphoma
NCT01354392 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Camrelizumab Plus Decitabine in Anti-PD-1 Treatment-naive Patients With Relapsed/Refractory Classical Hodgkin Lymphoma
NCT04510610 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Chidamide for Patients With Relapse or Refractory Diffuse Large B-Cell Lymphoma and Follicular Lymphoma
NCT03410004 ·Status: UNKNOWN ·Phase: PHASE2
-
SHR-1210 Alone or in Combination With Decitabine in Relapsed or Refractory Hodgkin Lymphoma
NCT03250962 ·Status: UNKNOWN ·Phase: PHASE2
-
Tumor-Specific Clonotype, Metabolic Profile, and PET/CT in Predicting Chemotherapy Response in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma
NCT02405078 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Romidepsin, Gemcitabine, Dexamethasone and Cisplatin in the Treatment of Peripheral T-Cell and Diffuse Large B-Cell Lymphoma
NCT01846390 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of GFH009 in Combination With Zanubrutinib in Subjects With Relapsed or Refractory DLBCL
NCT06375733 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Phase I-II Study in CD30 Positive Diffuse Large B-cell Lymphoma Patients Refractory to First Line Chemotherapy or in First Relapse
NCT03356054 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of GSK2816126 in Subjects With Relapsed/Refractory Diffuse Large B Cell Lymphoma, Transformed Follicular Lymphoma, Other Non-Hodgkin's Lymphomas, Solid Tumors and Multiple Myeloma
NCT02082977 ·Status: TERMINATED ·Phase: PHASE1
-
Study of the Impact of CD34+ Cell Dose on Absolute Lymphocyte Count Following High-Dose Therapy and Autologous Stem Cell Transplantation for Relapsed and Refractory Diffuse Large B-cell Lymphoma (DLBCL)
NCT02570542 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Copanlisib and Combination Chemotherapy for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma or Relapsed Grade 3b Follicular Lymphoma
NCT04156828 ·Status: TERMINATED ·Phase: PHASE1
-
Study to Evaluate the Efficacy and Safety of Camidanlumab Tesirine (ADCT-301) in Patients With Relapsed or Refractory Hodgkin Lymphoma
NCT04052997 ·Status: COMPLETED ·Phase: PHASE2
-
Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment
NCT05890352 ·Status: RECRUITING ·Phase: PHASE2
-
Patients With Relapsed or Refractory Diffuse Large B Cell Non Hodgkin Lymphomas
NCT01078922 ·Status: TERMINATED ·Phase: PHASE2