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Use of Bone Marrow Derived Stem Cell and G-CSF With Circulatory Assistance in the Treatment of DCM

NCT03572660 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2026-04-06

No results posted yet for this study

Summary

DCM Support is recruiting patients with dilated cardiomyopathy and heart failure symptoms. The goal of this clinical trial is to examine whether treatment with a patient's own stem cells can improve their heart function and alleviate heart failure symptoms.

* Stem cells will be collected from bone marrow in the patient's hip under local anaesthetic.
* The stem cells will be infused into the arteries that supply blood to the heart under local anaesthetic.
* A mini heart pump will be used to take the strain off the heart during the procedure.
* The follow-up involves a phone call at 1 month and clinic visits at 3 and 12 months

Conditions

  • Dilated Cardiomyopathy

Interventions

BIOLOGICAL

Bone marrow derived mononuclear cells and G-CSF

Intra-coronary infusion

Sponsors & Collaborators

  • Barts & The London NHS Trust

    lead OTHER

Principal Investigators

  • Anthony Mathur · Queen Mary University of London

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-12-24
Primary Completion
2030-03-31
Completion
2030-03-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03572660 on ClinicalTrials.gov