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The Effect of Low Pressure Pneumoperitoneum During Laparoscopic Colorectal Surgery on Innate Immune Homeostasis.

NCT03572413 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2021-11-03

No results posted yet for this study

Summary

Substudy of the RECOVER trial (a randomised controlled trial comparing the effect of low pressure pneumoperitoneum with deep neuromuscular block versus normal pressure pneumoperitoneum with moderate neuromuscular block during laparoscopic colorectal surgery on early quality of recovery) investigating innate immune homeostasis after laparoscopic colorectal surgery.

Conditions

  • Pneumoperitoneum
  • Neuromuscular Blockade
  • Surgery
  • Immune Suppression

Interventions

PROCEDURE

Low pressure pneumoperitoneum

Lowering intra-abdominal pressure during laparoscopic surgery

DRUG

Rocuronium bromide

Deep (PTC 1-2) versus moderate (TOF count 1-2) neuromuscular block

Sponsors & Collaborators

Principal Investigators

  • Kim I Albers, MD · Radboud University Medical Center

  • Michiel C Warlé, MD, PhD · Radboud University Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-10-24
Primary Completion
2020-08-31
Completion
2020-12-01

Countries

  • Netherlands

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03572413 on ClinicalTrials.gov