MedTrace Logo

Indicators of Growth, Nutritional Status and Comorbide Disorders of Newborns With Down Syndrome

NCT03553706 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 141

Last updated 2018-06-12

No results posted yet for this study

Summary

Objective To access predictive values of the auxological parameters and indexes for risk of comorbid malformations in newborns with Down syndrome (DS)

Study design In this cohort retrospective study, 141 newborns with proven trisomy 21 born at the Department of Gynecology and Obstetrics of the University of Split Hospital (1990 to 2015) were included. The data were obtained from the medical histories of mothers, infants and the delivery protocol.

The objective was to access predictive values of the auxological parameters and indexes for risk of comorbid malformations in newborns with Down syndrome (DS)

Conclusion Higher CI were found in hyportrophic (SGA) newborns with DS and indicated their intrauterine growth restriction with brain sparing and increased further risk of severe psychomotor retardation. The SGA newborns have lower parameters and indexes of nutritive status and significantly differed from eutrophic and hypertrophic newborns. These SGA newborns with DS have increased developmental risks and that requires further diagnostic attention.

Conditions

  • Down Syndrome,Auxological Indexes, Auxological Parametars, Intrauterine Growth Restriction

Sponsors & Collaborators

  • University Hospital of Split

    lead OTHER

Principal Investigators

  • Asija Rota Ceprnja, MD · University Hospital Split Department for Rehabilitation

Eligibility

Min Age
1 Day
Max Age
1 Month
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-05-20
Primary Completion
2018-05-30
Completion
2018-05-30

Countries

  • Croatia

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03553706 on ClinicalTrials.gov