DEP-Ru Regimen as a Salvage Therapy for HLH
NCT03533790 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 80
Last updated 2018-05-30
Summary
This study aimed to investigate the efficacy and safety of ruxolitinib together with liposomal doxorubicin, etoposide and methylprednisolone (DEP-Ru) as a salvage therapy for refractory/relapsed hemophagocytic lymphohistiocytosis.
Conditions
- Hemophagocytic Lymphohistiocytosis
Interventions
- DRUG
-
DEP-Ru
* Drug: ruxolitinib * Drug: doxorubicin * Drug: etoposide * Drug: methylprednisolone
Sponsors & Collaborators
-
Beijing Friendship Hospital
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 1 Year
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-06-30
- Primary Completion
- 2018-06-30
- Completion
- 2021-06-30
Countries
- China
Study Locations
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