Study of Changes in Retrofoveolar Choroidal Thickness During Aerobic Exercise

Summary

Study the change of retrofoveolar choroidal thickness measured by optical coherence tomography during aerobic exercise inducing an increase in systolic blood pressure in healthy subjects.Ten healthy participants will perform an exercise (riding a bicycle ergometer) and will be examined with EDI-OCT. Each participant will be scanned before exercise, during the exercise and afterwards at 0 and 5 min. Each OCT measurement will be coupled to the arterial blood pressure evaluation.

Conditions

• Choroid Disease
• Hypertension Ocular

Interventions

OTHER

Examination of pressures before stopping the exercise

In healthy volunteers performing aerobic physical exercise in the Department of Sports Medicine, the investigators will perform different examinations : * Macular and peri-papillary OCT in EDI mode (bilateral examination), * Intraocular pressure (bilateral examination) * Measurement of systolic and diastolic blood pressure * Heart rate measurement Exercise testing will be performed on bicycle measuring session with 10 minutes at moderate intensity ( 30% OF MPA), 10 minutes at sustained intensity ( 50% of MPA) and 3 minutes at maximum (70% of MPA). The theoretical maximal aerobic power was calculated by a mathematical formula.

OTHER

Examination of pressure during the exercise

In healthy volunteers performing aerobic physical exercise in the Department of Sports Medicine, the investigators will perform different examinations : * Macular and peri-papillary OCT in EDI mode (bilateral examination), * Intraocular pressure (bilateral examination) * Measurement of systolic and diastolic blood pressure * Heart rate measurement Exercise testing will be performed on bicycle measuring session with 10 minutes at moderate intensity ( 30% OF MPA), 10 minutes at sustained intensity ( 50% of MPA) and 3 minutes at maximum (70% of MPA). The theoretical maximal aerobic power was calculated by a mathematical formula.

OTHER

Examination of pressures after stopping the exercise

In healthy patients performing aerobic physical exercise in the Department of Sports Medicine, the investigators will perform different examinations : * Macular and peri-papillary OCT in EDI mode (bilateral examination), * Intraocular pressure (bilateral examination) * Measurement of systolic and diastolic blood pressure * Heart rate measurement Exercise testing will be performed on bicycle measuring session with 10 minutes at moderate intensity ( 30% OF MPA), 10 minutes at sustained intensity ( 50% of MPA) and 3 minutes at maximum (70% of MPA). The theoretical maximal aerobic power was calculated by a mathematical formula.

Sponsors & Collaborators

• University Hospital, Toulouse

  lead OTHER

Principal Investigators

• Vincent SOLER, MD · University Hospital, Toulouse

Study Design

Allocation

NA

Purpose

OTHER

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Sex

MALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2019-07-31

Primary Completion

2020-07-31

Completion

2020-07-31

Countries

• France

Study Locations