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Singapore PREconception Study of Long-Term Maternal and Child Outcomes

NCT03531658 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 1054

Last updated 2025-06-18

No results posted yet for this study

Summary

We aim to test the following primary hypothesis that nutrition, lifestyle, and maternal emotional health prior to pregnancy and/or during the first trimester alter the expression of metabolic or neurodevelopmental endophenotypes with accompanying effects on the epigenome/transcriptome of the offspring.

Conditions

  • Metabolic Disease
  • Neurological and Mental Health Conditions
  • Genetics Predisposition
  • Skin Condition
  • Environmental Exposure
  • Socioeconomic Factors
  • Psychology, Social

Sponsors & Collaborators

  • National University Health System, Singapore

    collaborator OTHER

  • Institute for Human Development and Potential (IHDP), Singapore

    collaborator OTHER

  • KK Women's and Children's Hospital

    lead OTHER_GOV

Principal Investigators

  • Jerry Kok Yen Chan · KK Women's and Children's Hospital

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-02-27
Primary Completion
2029-12-31
Completion
2029-12-31

Countries

  • Singapore

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03531658 on ClinicalTrials.gov