Trial Outcomes & Findings for NIHR CV Health Informatics Collaborative (NCT NCT03507309)

NCT ID: NCT03507309

Last Updated: 2024-10-08

Results Overview

Number of patients who died (from any cause) including in-hospital, short-term and long-term mortality

Recruitment status

ACTIVE_NOT_RECRUITING

Target enrollment

257948 participants

Primary outcome timeframe

Hospital admission to 3 years follow-up

Results posted on

2024-10-08

Participant Flow

Participant milestones

Participant milestones
Measure	Unselected Cohort of Patients Who Had a Troponin Measured A total of 257 948 patients who presented to hospital during the study period (2010-17) and had at least one troponin blood test measured.
Overall Study STARTED	257948
Overall Study COMPLETED	257948
Overall Study NOT COMPLETED	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

NIHR CV Health Informatics Collaborative

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Unselected Cohort of Patients Who Had a Troponin Measured n=257948 Participants A total of 257 948 patients who presented to hospital during the study period (2010-17) and had at least one troponin blood test measured.
Age, Continuous	65 years n=99 Participants
Sex: Female, Male Female	115230 Participants n=99 Participants
Sex: Female, Male Male	142718 Participants n=99 Participants
Race/Ethnicity, Customized White	147321 Participants n=99 Participants
Race/Ethnicity, Customized South Asian	7169 Participants n=99 Participants
Race/Ethnicity, Customized Black	19925 Participants n=99 Participants
Race/Ethnicity, Customized Other	23401 Participants n=99 Participants
Race/Ethnicity, Customized Missing	60132 Participants n=99 Participants
Region of Enrollment United Kingdom	257948 participants n=99 Participants

PRIMARY outcome

Timeframe: Hospital admission to 3 years follow-up

Number of patients who died (from any cause) including in-hospital, short-term and long-term mortality

Outcome measures

Outcome measures
Measure	Unselected Cohort of Patients Who Had a Troponin Measured n=257948 Participants A total of 257 948 patients who presented to hospital during the study period (2010-17) and had at least one troponin blood test measured.
Mortality, All-cause	55850 Participants

SECONDARY outcome

Timeframe: 3 months follow-up

Population: 134,517 accounts for the number of patients 'admitted' to hospital, who had a troponin measured.

Acute revascularisation will be defined as having PCI or CABG in the time window between 48 hours before and 3 months after the first troponin measurement. This will account for patients who had revascularisation, in particular PCI, as an emergency prior to their first troponin blood test and to capture revascularisation, in particular CABG, performed as an outpatient following their index admission.

Outcome measures

Outcome measures
Measure	Unselected Cohort of Patients Who Had a Troponin Measured n=134517 Participants A total of 257 948 patients who presented to hospital during the study period (2010-17) and had at least one troponin blood test measured.
Acute Revascularisation	17444 Participants

Adverse Events

Unselected Cohort of Patients Who Had a Troponin Measured

Serious events: 0 serious events

Other events: 0 other events

Deaths: 55850 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr Amit Kaura

Imperial College Healthcare NHS Trust

Phone: 020 3312 6666

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place