Precise Treatment System of Biliary Malignancies Based on Special Disease Database

Summary

Malignant tumors of biliary system lack standard treatment and precise prognosis assessment methods. This study including 12 hospitals, collecting clinical and follow-up data of patients with biliary malignant tumors including cholangiocarcinoma and gallbladder carcinoma in recent 10 years, aim to build a special disease database, then use Bayesian networks and importance theory to establish a mathematical model to assess treatment strategies and prognosis accurately. At the same time, data on biliary malignant tumors newly treated by multicenters from 2018 to 2020 will be included to validate, adjust and refine the models to guide clinical individualized precise treatment.

Conditions

• Cholangiocarcinoma
• Gall Bladder Carcinoma
• Biliary System Disorder

Sponsors & Collaborators

• First Affiliated Hospital Xi'an Jiaotong University

  collaborator OTHER

• The First Affiliated Hospital of Zhengzhou University

  collaborator OTHER

• The First Affiliated Hospital of Dalian Medical University

  collaborator OTHER

• Shanghai Zhongshan Hospital

  collaborator OTHER

• Southwest Hospital, China

  collaborator OTHER

• Tianjin Medical University Cancer Institute and Hospital

  collaborator OTHER

• Sun Yat-sen University

  collaborator OTHER

• Affiliated Hospital of North Sichuan Medical College

  collaborator OTHER

• The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

  collaborator OTHER

• Second Affiliated Hospital, School of Medicine, Zhejiang University

  collaborator OTHER

• Eastern Hepatobiliary Surgery Hospital

  collaborator OTHER

• Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

  lead OTHER

Principal Investigators

• Zhimin Geng, MD,PhD · the first affiliated hospital of xi'an Jiaotong univerisity

• Peng Gong, MD,PhD · the first affiliated hospital of Dalian medical univerisity

• Yu He, MD,PhD · Southwest Hospital, China

• Shengping Li, MD,PhD · Cancer Institute and Hospital Affiliated to Sun Yat-sen University

• Yinghe Qiu, MD,PhD · Eastern Hepatobiliary Surgery Hospital

• Zhi Dai, MD,PhD · Shanghai Zhongshan Hospital

• Tianqiang Song, MD,PhD · Tianjin Medical University Cancer Institute and Hospital

• Yudong Qiu, MD,PhD · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

• Jianying Lou, MD,PhD · Second Affiliated Hospital, School of Medicine, Zhejiang University

• Jingdong Li, MD,PdD · Affliated Hospital of North Sichuan Medical College

• Wenlong Zhai, MD,PhD · The First Affiliated Hospital of Zhengzhou University

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2018-05-25

Primary Completion

2021-08-31

Completion

2021-12-31

Countries

• China

Study Locations