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Interaction Between Non-typhoid Salmonella, Host Microbiota, and Immune System During Acute Infection and Remission

NCT03494101 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2018-07-03

No results posted yet for this study

Summary

Stool and blood samples from patients with a non-typhoid Salmonella infection will be collected during an observation period of six months and analyzed for changes in the microbiota diversity and composition, mutation rates in the Salmonella strains and the specific immune response evoked by the infection. Findings are compared to healthy individuals and individuals with acute, infectious diarrhea caused by other microorganisms.

Conditions

  • Salmonella Infection Non-Typhoid

Interventions

OTHER

Blood samples

Blood samples will be collected and analyzed at different study time points

OTHER

Stool samples

Stool samples will be collected and analyzed at different study time points

OTHER

Clinical information

Clinical information will be collected at different study time points using questionnaires

Sponsors & Collaborators

  • University of Zurich

    lead OTHER

Principal Investigators

  • Benjamin Misselwitz, PD Dr.med. · Division of Gastroenterology, University Hospital Zurich Zurich, Switzerland, 8091

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-06-15
Primary Completion
2020-01-31
Completion
2020-01-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03494101 on ClinicalTrials.gov