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Systemic Lidocaine Infusion for Pain Control in Ventral Hernia

NCT03484650 · Status: WITHDRAWN · Phase: PHASE3 · Type: INTERVENTIONAL

Last updated 2021-02-01

No results posted yet for this study

Summary

Ventral hernia repair leads to more than expected pain. This is thought to be secondary to nerve pain at the lateral transfixion sutures. Systemic lidocaine given pre-op has in other situations decreased neurogenic pain. This study will examine its effects on pain experienced after ventral hernia repair.

Conditions

  • Post Operative Pain

Interventions

DRUG

Lidocaine Hydrochloride

Lidocaine bolus to be given 1 hour pre-operatively

DRUG

Lidocaine Hydrochloride

Lidocaine infusion will be started after the bolus and be continued for 24 hours post-operatively

OTHER

Placebo

Control patients will receive a placebo bolus and infusion of saline to match the experimental arm.

Sponsors & Collaborators

  • Carilion Clinic

    lead OTHER

Principal Investigators

  • Sandy L Fogel, MD · Carilion Clinic

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-01-14
Primary Completion
2022-12-01
Completion
2022-12-01
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03484650 on ClinicalTrials.gov