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The Effectiveness of Vancomycin in Comarison With Cefazolin in Prevention of SSI After Craniotomy

NCT03466645 · Status: UNKNOWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 126

Last updated 2018-03-15

No results posted yet for this study

Summary

Surgical-site infection is the most commonly reported nosocomial infection in patients undergoing surgery and 3rd most nosocomial infection in hospitalized patients. The SSI is associated with increases of length of hospitalization for 6 days and increases the hospital's cost by $ 300.

Because of these, prevention of SSI with appropriate antibiotic is essential.

Conditions

  • Elective Craniotomy-candidated Patients

Interventions

DRUG

Vancomycin

The 1st group receives vancomycin an hour before craniotomy

DRUG

Cefazolin

The 2nd group receives cefazolin an hour before craniotomy

Sponsors & Collaborators

  • Isfahan University of Medical Sciences

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-04-01
Primary Completion
2019-04-01
Completion
2019-08-01

Countries

  • Iran

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03466645 on ClinicalTrials.gov