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Spinal and Supra-Spinal Pain Mechanisms in Patients With Fibromyalgia

NCT03464292 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 55

Last updated 2023-12-14

No results posted yet for this study

Summary

Fibromyalgia (FM) patients have increased windup (WU). However, WU of FM patients is only quantitatively but not qualitatively different from healthy controls (HC). Thus WU abnormalities of FM patients could be the result of supra-spinal and not the result of spinal pain mechanisms. The study team will test this hypothesis by sensitizing FM patients with topical capsaicin.

Conditions

Interventions

DRUG

Capsaicin Patch 8% or 0.1% Capsaicin Cream

0.1 ml of 8% capsaicin topical patch or 0.1% capsaicin cream

OTHER

Vehicle Patch

Control patch will be the same topical solution but will not contain capsaicin.

Sponsors & Collaborators

  • University of Florida

    lead OTHER

Principal Investigators

  • Roland Staud, MD · University of Florida

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-07-05
Primary Completion
2023-07-01
Completion
2023-12-08

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03464292 on ClinicalTrials.gov