Trial Outcomes & Findings for 3D Printed Models in Mohs Micrographic Surgery (NCT NCT03461965)

NCT ID: NCT03461965

Last Updated: 2021-05-21

Results Overview

This is an in-house-designed, short questionnaire with 6 multiple choice objective questions related to the participant's understanding of Mohs. A higher percentage of correct answers indicate a better understanding of Mohs. Reported data are percent of responses answered correctly and incorrectly totaled across all participants in each arm

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

82 participants

Primary outcome timeframe

Post surgery (1 day)

Results posted on

2021-05-21

Participant Flow

Participant milestones

Participant milestones
Measure
Education With 3D Printed Model
The experimental group will be educated on MMS with a standardized script in addition to a 3D MMS model 3D printed model: A printed 3D model of Mohs Micrographic Surgery will be created showing a model of skin, and a tumor to visually depict the surgery Verbal Counselling: patients will be educated with a standardized script on skin cancer, risks for skin cancer, treatment options, and Mohs Micrographic Surgery
Verbal Counselling
Participants in the control group will be educated on MMS according to the current standard of care, verbal counselling, with a standardized script Verbal Counselling: patients will be educated with a standardized script on skin cancer, risks for skin cancer, treatment options, and Mohs Micrographic Surgery
Overall Study
STARTED
42
40
Overall Study
COMPLETED
42
40
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Education With 3D Printed Model
n=42 Participants
The experimental group will be educated on MMS with a standardized script in addition to a 3D MMS model 3D printed model: A printed 3D model of Mohs Micrographic Surgery will be created showing a model of skin, and a tumor to visually depict the surgery Verbal Counselling: patients will be educated with a standardized script on skin cancer, risks for skin cancer, treatment options, and Mohs Micrographic Surgery Participants in the control group will be educated on MMS according to the current standard of care, verbal counselling, with a standardized script Verbal Counselling: patients will be educated with a standardized script on skin cancer, risks for skin cancer, treatment options, and Mohs Micrographic Surgery
Verbal Counselling
n=40 Participants
Participants in the control group will be educated on MMS according to the current standard of care, verbal counselling, with a standardized script Verbal Counselling: patients will be educated with a standardized script on skin cancer, risks for skin cancer, treatment options, and Mohs Micrographic Surgery
Total
n=82 Participants
Total of all reporting groups
Age, Continuous
67.83 Years
STANDARD_DEVIATION 11.34 • n=42 Participants
67.83 Years
STANDARD_DEVIATION 12.89 • n=40 Participants
67.83 Years
STANDARD_DEVIATION 12.10 • n=82 Participants
Sex: Female, Male
Female
18 Participants
n=42 Participants
15 Participants
n=40 Participants
33 Participants
n=82 Participants
Sex: Female, Male
Male
24 Participants
n=42 Participants
25 Participants
n=40 Participants
49 Participants
n=82 Participants
Race and Ethnicity Not Collected
0 Participants
Race and Ethnicity were not collected from any participant.
Region of Enrollment
United States
42 participants
n=42 Participants
40 participants
n=40 Participants
82 participants
n=82 Participants
Previous MMS experience
Mohs Experience
20 Participants
n=42 Participants
19 Participants
n=40 Participants
39 Participants
n=82 Participants
Previous MMS experience
No Mohs Experience
22 Participants
n=42 Participants
21 Participants
n=40 Participants
43 Participants
n=82 Participants
Baseline STAI Y-2 "Trait Anxiety"
29.8 units on a scale
STANDARD_DEVIATION 7.53 • n=42 Participants
31.1 units on a scale
STANDARD_DEVIATION 8.85 • n=40 Participants
30.5 units on a scale
STANDARD_DEVIATION 8.25 • n=82 Participants

PRIMARY outcome

Timeframe: Post surgery (1 day)

This is an in-house-designed, short questionnaire with 6 multiple choice objective questions related to the participant's understanding of Mohs. A higher percentage of correct answers indicate a better understanding of Mohs. Reported data are percent of responses answered correctly and incorrectly totaled across all participants in each arm

Outcome measures

Outcome measures
Measure
Education With 3D Printed Model
n=42 Participants
The experimental group will be educated on MMS with a standardized script in addition to a 3D MMS model 3D printed model: A printed 3D model of Mohs Micrographic Surgery will be created showing a model of skin, and a tumor to visually depict the surgery Verbal Counselling: patients will be educated with a standardized script on skin cancer, risks for skin cancer, treatment options, and Mohs Micrographic Surgery
Verbal Counselling
n=40 Participants
Participants in the control group will be educated on MMS according to the current standard of care, verbal counselling, with a standardized script Verbal Counselling: patients will be educated with a standardized script on skin cancer, risks for skin cancer, treatment options, and Mohs Micrographic Surgery
Percent of Correct and Incorrect Mohs Quiz Responses
Correct Quiz Responses
93.25 Percent of quiz responses
85.83 Percent of quiz responses
Percent of Correct and Incorrect Mohs Quiz Responses
Incorrect Quiz Responses
6.75 Percent of quiz responses
14.17 Percent of quiz responses

SECONDARY outcome

Timeframe: From baseline to post surgery (1 day)

The STAI is a well-known, frequently used measure of patient anxiety within the clinical setting. This form consists of two forms to assess state anxiety (Y-1) and a participant's baseline trait anxiety (Y-2). The Y-1 form consists of 20 Likert-type questions with scores ranging from 20 to 80, with higher scores indicating higher anxiety. Reported values are change in "state anxiety' (post-stage minus baseline)

Outcome measures

Outcome measures
Measure
Education With 3D Printed Model
n=42 Participants
The experimental group will be educated on MMS with a standardized script in addition to a 3D MMS model 3D printed model: A printed 3D model of Mohs Micrographic Surgery will be created showing a model of skin, and a tumor to visually depict the surgery Verbal Counselling: patients will be educated with a standardized script on skin cancer, risks for skin cancer, treatment options, and Mohs Micrographic Surgery
Verbal Counselling
n=40 Participants
Participants in the control group will be educated on MMS according to the current standard of care, verbal counselling, with a standardized script Verbal Counselling: patients will be educated with a standardized script on skin cancer, risks for skin cancer, treatment options, and Mohs Micrographic Surgery
Change in State-Trait Anxiety Inventory (STAI) Y-1 (State Anxiety) Score
-4.95 Score on a scale
Standard Deviation 6.95
-3.3 Score on a scale
Standard Deviation 9.37

SECONDARY outcome

Timeframe: From baseline to post surgery (1 day)

The VAS is a frequently employed Likert-type scale that is used to measure anxiety. This 0-10 scale documents the patients current state of anxiety, with higher scores indicating worse anxietey, and can be answered by patients with an average reading level. Estimated time of completion is under 30 seconds. This form has been used in 2 studies to date and previously by experimental team to assess intraoperative anxiety in Mohs.

Outcome measures

Outcome measures
Measure
Education With 3D Printed Model
n=42 Participants
The experimental group will be educated on MMS with a standardized script in addition to a 3D MMS model 3D printed model: A printed 3D model of Mohs Micrographic Surgery will be created showing a model of skin, and a tumor to visually depict the surgery Verbal Counselling: patients will be educated with a standardized script on skin cancer, risks for skin cancer, treatment options, and Mohs Micrographic Surgery
Verbal Counselling
n=40 Participants
Participants in the control group will be educated on MMS according to the current standard of care, verbal counselling, with a standardized script Verbal Counselling: patients will be educated with a standardized script on skin cancer, risks for skin cancer, treatment options, and Mohs Micrographic Surgery
Change in Visual Analog Scale (VAS) Anxiety Score
-1.31 Score on a scale
Standard Deviation 2.00
-0.53 Score on a scale
Standard Deviation 1.54

SECONDARY outcome

Timeframe: From baseline to post surgery (1 day)

The VAS is a frequently employed Likert-type scale that because of the ease of use this tool has been converted to assess other objective measures including understanding. This 0-10 scale documents the participant's current state of understanding, with higher scores indicating better understanding, and can be answered by patients with an average reading level. Estimated time of completion is under 30 seconds. This form has been used by experimental team to assess intraoperative understanding in Mohs.

Outcome measures

Outcome measures
Measure
Education With 3D Printed Model
n=42 Participants
The experimental group will be educated on MMS with a standardized script in addition to a 3D MMS model 3D printed model: A printed 3D model of Mohs Micrographic Surgery will be created showing a model of skin, and a tumor to visually depict the surgery Verbal Counselling: patients will be educated with a standardized script on skin cancer, risks for skin cancer, treatment options, and Mohs Micrographic Surgery
Verbal Counselling
n=40 Participants
Participants in the control group will be educated on MMS according to the current standard of care, verbal counselling, with a standardized script Verbal Counselling: patients will be educated with a standardized script on skin cancer, risks for skin cancer, treatment options, and Mohs Micrographic Surgery
Change in Visual Analog Scale (VAS) Understanding Score
1.83 Score on a scale
Standard Deviation 2.22
2.46 Score on a scale
Standard Deviation 2.34

SECONDARY outcome

Timeframe: Post surgery (1 day)

Participants were provided 3 subjective questions related to their satisfaction with the explanation of MMS that they received. This scale included questions regarding satisfaction with their explanation of the MMS procedure, if the explanation used could be improved, and if they recommended other patients be provided a similar explanation of MMS, with each question scored from 1 to 5, with higher scores indicating greater satisfaction. Total score range is 0 to 15, with higher scores indicating greater satisfaction.

Outcome measures

Outcome measures
Measure
Education With 3D Printed Model
n=42 Participants
The experimental group will be educated on MMS with a standardized script in addition to a 3D MMS model 3D printed model: A printed 3D model of Mohs Micrographic Surgery will be created showing a model of skin, and a tumor to visually depict the surgery Verbal Counselling: patients will be educated with a standardized script on skin cancer, risks for skin cancer, treatment options, and Mohs Micrographic Surgery
Verbal Counselling
n=40 Participants
Participants in the control group will be educated on MMS according to the current standard of care, verbal counselling, with a standardized script Verbal Counselling: patients will be educated with a standardized script on skin cancer, risks for skin cancer, treatment options, and Mohs Micrographic Surgery
Satisfaction Survey Score
14.69 score on a scale
Standard Deviation 0.811
13.58 score on a scale
Standard Deviation 1.599

Adverse Events

Education With 3D Printed Model

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Verbal Counselling

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Margaret Mann, MD

University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center

Phone: 1-800-641-2422

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place