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Prospective Assessment of Radiation-induced Heart Injury in Left-sided Breast Cancer

NCT03461588 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 140

Last updated 2020-03-25

No results posted yet for this study

Summary

This study is to prospectively investigate the cardiac dose-sparing effect and clinical benefit of deep inspiration breath-hold (DIBH) technique. Patients with left-sided breast cancer treated with breast conserving surgery followed by radiotherapy is enrolled. Radiotherapy is delivered with either free-breathing or deep inspiration breath-hold (DIBH) technique. The cardiac dose parameters and cardiac toxicity are prospective evaluated, and the dose-effect relationship is analyzed.

Conditions

  • Breast Neoplasms
  • Heart Injuries
  • Radiation Toxicity

Interventions

RADIATION

free-breathing

patients are irradiated to whole breast +- regional nodal areas with free-breathing technique after breast conserving surgery

RADIATION

deep inspiratory breath-holding

patients are irradiated to whole breast +- regional nodal areas with deep inspiratory breast-holding technique after breast conserving surgery

Sponsors & Collaborators

  • Shu lian Wang

    lead UNKNOWN

Principal Investigators

  • Shulian Wang, M.D. · Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-01-01
Primary Completion
2020-01-30
Completion
2020-01-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03461588 on ClinicalTrials.gov