MedTrace Logo

Fecal Microbiota Alterations in Steroid Refractory Active Colitis Ulcerosa

NCT03460847 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 114

Last updated 2021-09-08

No results posted yet for this study

Summary

Alterations in the intestinal microbiota have been associated to disease pathogenesis in ulcerative colitis. Refractory disease to standard medical therapy as corticosteroids often leads to an unfavourable course in patients suffering from this disorder. This study proposal aims at investigating changes in the intestinal microbiota that can predict a therapy refractory course of ulcerative colitis (UC) and may be used to identify high risk patients in an early phase of their disease.

Conditions

  • Colitis, Ulcerative

Interventions

DRUG

Steroids

Patients with active colitis ulcerosa who need steroids because of their disease course. 1mg/kg bodyweight for one week, followed by a tapping periode.

Sponsors & Collaborators

  • Medical University of Graz

    lead OTHER

Principal Investigators

  • Christoph Hoegenauer, Prof. · Medical University of Graz

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-03-01
Primary Completion
2021-03-01
Completion
2021-03-01

Countries

  • Austria

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03460847 on ClinicalTrials.gov